Our LC-MS testing services cover a broad spectrum of applications, including small molecule analysis, peptide and protein characterization, impurity profiling, and trace-level detection. Combining cutting-edge instrumentation with a highly experienced technical team, we provide precise and reliable results, supported by comprehensive analytical reports tailored to project-specific requirements. Clients value our consistent professionalism, dependable service, and timely technical support.
Liquid Chromatography-Mass Spectrometry (LC-MS) is a powerful analytical technique that integrates liquid chromatography (LC) with mass spectrometry (MS). LC separates sample mixtures into individual components based on chemical properties, while MS identifies and characterizes each component according to its mass-to-charge ratio. This combination enables highly sensitive analysis of complex samples, delivering accurate molecular information such as molecular weight, structural characteristics, and component composition. LC-MS is widely employed in research and industrial applications as a key method for molecular identification and component analysis.
Provides targeted mass analysis using single quadrupole mass filters, enabling full scan and selected ion monitoring (SIM). Ideal for quantitative determination of small molecules, impurity profiling, and routine sample screening. At BOC Sciences, instrument parameters are optimized for sensitivity and reproducibility to deliver reliable, high-quality data for analytical and research purposes.
Enables multiple reaction monitoring (MRM) for highly sensitive and selective quantification. Perfect for trace-level detection, metabolite analysis, and residue testing. At BOC Sciences, method development focuses on achieving optimal detection limits and robust quantitation, supporting precise measurement in complex matrices.
Combines the quantitative capabilities of a triple quadrupole with the structural elucidation power of ion traps. Suitable for comprehensive metabolite profiling and complex sample analysis. At BOC Sciences, experiments are tailored to maximize information from both MS and MS/MS spectra, ensuring high confidence in molecular identification.
Provides multi-stage MSn fragmentation for detailed structural analysis. Ideal for elucidation of unknown compounds and characterization of complex molecules. At BOC Sciences, workflows are optimized to capture rich fragmentation patterns, supporting structure confirmation and mechanistic studies.
Offers high-resolution, accurate mass measurements for full scan analysis. Suitable for metabolomics, natural product identification, and precise molecular weight determination. At BOC Sciences, TOF methods are refined to deliver high mass accuracy and reproducible results for advanced analytical applications.
Delivers ultra-high resolution and precise mass accuracy, enabling in-depth molecular characterization. Ideal for proteomics, metabolomics, and complex mixture analysis. At BOC Sciences, Orbitrap workflows are designed to provide comprehensive data sets with exceptional mass precision, supporting cutting-edge research and discovery.
Connect with our team to explore the most efficient LC-MS strategies for molecular characterization, quantification, and profiling.
Provide your sample type, amount, and preparation details. Receive a customized testing quote.
LC-MS plays a critical role in drug metabolism studies, pharmacokinetic analysis, metabolite profiling, and biopharmaceutical characterization. Pharmaceutical and biotech organizations often encounter challenges such as complex biological matrices and low-abundance analytes. Our LC-MS testing services deliver accurate qualitative and quantitative insights, supporting drug discovery, process optimization, and consistent evaluation of product quality across diverse projects.
Food and nutrition companies utilize LC-MS to detect contaminants, pesticide residues, veterinary drug residues, and quantify functional ingredients. Common analytical challenges include complex sample matrices, trace-level detection, and high-throughput testing demands. Our LC-MS services provide sensitive, precise, and dependable results, supporting product safety verification, quality assurance, and nutritional analysis.
LC-MS is increasingly applied in the development of diagnostic assays for biomarkers, metabolites, and therapeutic monitoring. Diagnostic developers face challenges such as low-abundance analytes, matrix interferences, and the need for reproducible quantitative data. Our services provide high-resolution, accurate measurements, enabling robust assay development, biomarker validation, and reliable performance evaluation.
Researchers use LC-MS for metabolomics, proteomics, lipidomic, and complex sample analysis. Limited access to high-end instrumentation, small sample volumes, and high data quality requirements often create bottlenecks. Our LC-MS services provide access to high-sensitivity, high-accuracy analyses, supporting experimental design, comprehensive sample evaluation, and reliable scientific outcomes across multiple research disciplines.
Whether for pharmaceutical R&D, food safety assurance, diagnostic development, or academic research, our LC-MS services deliver accurate and reproducible analytical data. Connect with our experts to design a customized testing plan that accelerates your research, development, and quality objectives.
Clients contact us via form, email, or phone, providing sample information. Our team confirms analysis goals and special requirements for accurate testing solutions.
Clients submit samples following guidance. Upon arrival, samples are logged, checked for integrity, and prepared for LC-MS analysis under secure handling.
Our analysts develop a customized LC-MS testing plan, including separation strategy, mass spectrometry mode, and data acquisition method, ensuring reliable results.
Samples are analyzed following the designed protocol. Data is recorded securely and monitored for completeness, accuracy, and experimental consistency.
Analysts process and interpret results, generating a clear report with technical insights, charts, and a summary for comprehensive sample understanding.
Final reports are delivered electronically. Our team provides guidance, answers client questions, and suggests follow-up analyses for valuable testing insights.
Our LC-MS testing reveals detailed molecular structures and interactions, providing clients with an in-depth understanding beyond basic identification or quantification.
We deliver precise detection of trace components and low-abundance analytes, ensuring reliable, reproducible results even for challenging or complex samples.
BOC Sciences designs customized LC-MS workflows to address unique sample characteristics, maximizing data quality while minimizing experimental complexity.
Our approach quickly identifies analytical challenges and implements optimized strategies, accelerating project progression and enabling informed decision-making.
Our LC-MS solutions provide comprehensive support for a variety of applications, enabling accurate analysis in pharmacokinetics, impurity profiling, and product quality assessment.
Client: A specialty biochemical research company
Challenge: The client required precise detection and quantification of a broad range of metabolites in complex biochemical samples, including low-abundance components.
Solution: BOC Sciences implemented targeted and untargeted LC-MS workflows, combining high-performance chromatographic separation with sensitive mass detection. Our team optimized gradient conditions, MS fragmentation, and data deconvolution techniques to maximize coverage and minimize matrix effects. High-quality spectral reports and quantitative tables were provided for comprehensive metabolite profiling.
Outcome: The client achieved enhanced sensitivity and reproducibility, with accurate multi-metabolite detection, supporting advanced biochemical research and product development initiatives.
Client: A leading environmental testing laboratory in Europe
Challenge: The client required highly sensitive detection of trace organic contaminants in water and soil samples, where complex sample matrices often interfered with conventional analysis.
Solution: BOC Sciences deployed advanced LC-MS systems with high-resolution mass spectrometers. Our team optimized chromatographic separation using tailored column chemistries and gradient programs, while fine-tuning mass spectrometric parameters for precise multi-component detection. Comprehensive data analysis pipelines were applied to generate accurate quantitative reports and detailed spectra.
Outcome: The client achieved significantly improved detection sensitivity, efficient differentiation of overlapping compounds, and rapid reporting, enabling robust environmental monitoring and assessment.
Client: A multinational food ingredient manufacturer
Challenge: The client needed accurate profiling of complex mixtures of food additives and flavor compounds, where traditional methods lacked specificity and resolution.
Solution: BOC Sciences applied liquid chromatography coupled with mass spectrometry to separate and identify multiple additives simultaneously. We optimized sample preparation, mobile phase composition, and MS ionization modes, producing high-resolution chromatograms and quantitative spectral data. Our integrated workflow allowed simultaneous qualitative and quantitative analysis with minimal interference.
Outcome: The client gained reliable identification and quantification of multiple additives in a single run, improved analytical throughput, and enhanced confidence in product formulation decisions.
BOC Sciences' LC-MS testing provides highly reliable analytical results that significantly enhance our compound characterization efforts. The team's attention to method optimization and peak identification allows us to make informed decisions with confidence.
— Dr. M., Senior Scientist, Pharmaceutical R&D Firm
The LC-MS services from BOC Sciences combine cutting-edge instrumentation with expert data interpretation. Their detailed reports and thorough spectral analysis help us efficiently track molecular changes across complex samples.
— Dr. S., Research Chemist, Specialty Chemicals Company
BOC Sciences' LC-MS testing offers comprehensive analytical support that exceeds expectations. Their methodical approach to signal detection and fragmentation analysis has greatly aided our internal research workflows.
— Dr. J., Principal Scientist, Biotech Start-u
Using BOC Sciences' LC-MS testing, we consistently receive data we can rely on for decision-making. Their precise mass spectrometry profiling and attentive review process provide clarity for challenging analytical projects.
— Dr. K., Head of Analytical Development, Life Sciences Company
