Custom Lipid Synthesis

Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways.

As one of the leading companies in the field of custom synthesis, BOC Sciences has extensive experience in lipid design and lipid synthesis. Our expert team is always ready to solve any synthetic problems and provide the highest quality products for the smooth conduction of your research.

Lipid structure representation. (Fahy, E.; et al. 2011)

Lipid Synthesis Site in vivo

Lipid synthesis in the body is a complex process that plays a key role in cellular metabolism and biological function. Common lipid synthesis sites:

• Fatty acid synthesis occurs primarily in the cytoplasm at the fatty acid synthase complex, which is known as fatty acid synthase (FAS). Fatty acid synthesis is the process of converting acetyl-coenzyme A (Acetyl-CoA) into long-chain fatty acids.
• Phospholipid synthesis occurs mainly in phospholipid synthase on the endoplasmic reticulum (ER) or mitochondrial phospholipid synthase (MPS) on the mitochondrial membrane. Phospholipids are major components of cell membranes and are essential for cell structure and function.
• Steroid synthesis mostly occurs in the squalene synthase in the endoplasmic reticulum or in the farnesyl pyrophosphate synthase on the Golgi apparatus. Steroids play important roles in cell membrane structure and cell signaling.

Application of Lipids

Lipids have a wide range of applications in biology, medicine and industry. Here are some of the applications of lipids:

Biological Research: Lipids are used in various research applications, such as in lipidomics, the study of lipids and their functions in biological systems. Lipids are also used as model systems to study the properties of biological membranes.

Drug Delivery: Liposomes are tiny lipid vesicles that can be used to encapsulate drugs (e.g. siRNAs, chemotherapeutic small molecules, ASOs, etc.) in order to enhance the stability of the drug and improve its delivery to specific tissues or cells.

Industrial Applications: Lipids are used in various industrial applications, such as in the production of biodiesel and as emulsifiers in food and cosmetic industries.

Liposome applications in drug delivery. (Rumiana, T.; et al. 2021)

BOC Sciences' Custom Lipid Synthesis Services

BOC Sciences can design and synthesize different types of lipids according to customers' requirements. Our featured services for custom lipid synthesis include:

Fatty Acids Synthesis: These are the building blocks of most lipids. They can be saturated or unsaturated.

Triglycerides Synthesis: These are the most common type of fat found in food and in the body.

Phospholipids Synthesis: These are the main components of cell membranes. They have a hydrophilic (water-loving) head and a hydrophobic (water-repelling) tail.

Steroids Synthesis: These are a group of lipids with a distinctive four-ring structure.

Glycolipids Synthesis: These are lipids with a carbohydrate attached to them. They are important components of cell membranes and can also have signaling functions.

Lipoproteins Synthesis: These are complexes of lipids and proteins that transport lipids in the blood and are important for lipid metabolism.

In addition to common lipids synthesis, we also provide some modified lipid synthesis services:

• PEGylated lipids
• Fluorescent lipids
• Biotinylated lipids
• Halogenated lipids
• Oxidized lipids

Lipid Purification & Analysis

The purification of lipids usually involves a combination of different techniques such as extraction, chromatography, and precipitation. However, the analysis of lipids can provide valuable information about the composition and function of cell membranes, energy storage, and signaling pathways. BOC Sciences' available lipid purification and analysis techniques include:

Overall, the synthesis of lipids is a complex process involving a series of steps from design, organic synthesis and purification. BOC Sciences can provide a variety of lipid synthesis services. BOC Sciences is committed to providing you with optimized and customized lipid synthesis services to accelerate your research in lipid-related biology and development of drug delivery systems. Please feel free to contact us, the expertise of BOC Sciecnces' scientists, engineers and support team are at your disposal!