At BOC Sciences, we provide comprehensive High-Resolution Mass Spectrometry (HRMS) testing services to support diverse research and development needs across the biochemical, pharmaceutical, and industrial sectors. Our advanced HRMS platforms deliver precise molecular characterization, enabling detailed structural elucidation, accurate mass measurement, and complex mixture analysis. With a team of experienced scientists and a track record of reliable performance, we help clients accelerate discovery, enhance data confidence, and achieve higher efficiency in their projects. Our clients consistently recognize us for technical excellence, responsive collaboration, and trusted analytical solutions.
HRMS testing is an advanced analytical method that provides highly accurate measurements of molecular ions by separating them based on their precise mass-to-charge (m/z) ratios. Unlike conventional mass spectrometry, HRMS employs refined resolving power to distinguish molecules with nearly identical nominal masses, enabling exact molecular formula assignment and isotopic pattern recognition. The principle relies on generating ions from a sample, accelerating them through electromagnetic fields, and detecting their flight time or frequency, which is then translated into exact mass data. This high resolution not only facilitates structural elucidation of complex compounds but also enhances confidence in identifying trace components within multifaceted biochemical or industrial samples.
We offer the following HRMS testing services to support precise analysis of molecular structures and composition in your samples.
At BOC Sciences, we provide standard HRMS testing for accurate molecular weight determination and structural characterization of various compounds. This service ensures reliable data for research and development projects across biochemical, pharmaceutical, and industrial applications. Typical applications include general compound analysis, impurity profiling, and structural verification.
Our LC-HRMS service combines high-resolution mass spectrometry with liquid chromatography separation, ideal for non-volatile and polar compounds. With high sensitivity and excellent resolution, it is widely used for drug impurity analysis, herbal component identification, food safety testing, and peptide drug quality control.
GC-HRMS is tailored for volatile and thermally stable compounds. By integrating gas chromatography separation with high-resolution mass spectrometry detection, this service effectively analyzes environmental pollutants, food additives, and halogenated organic compounds, providing accurate trace component identification.
UHPLC-HRMS enhances separation efficiency for trace-level or complex matrix samples. This method combines speed and sensitivity, making it suitable for rapid screening of complex biochemical, pharmaceutical, or industrial samples. Typical applications include trace-level compound detection, high-throughput screening, and complex mixture analysis.
BOC Sciences can help. Our team will assess your requirements and provide a customized testing strategy with a clear, personalized quotation.
Submit your sample now and get your free, fast quotation in no time!
BOC Sciences provides HRMS testing for drug metabolism and pharmacokinetics, including metabolite identification and quantification. Our high-precision analysis supports complex biological samples, delivering reliable qualitative and quantitative data for drug discovery, development, and process optimization.
We offer high-resolution HRMS testing for environmental pollutants such as PFAS, pesticides, and polycyclic aromatic hydrocarbons (PAHs). Our sensitive methods ensure accurate detection of trace contaminants in water, soil, and industrial samples, supporting environmental safety and monitoring projects.
BOC Sciences performs HRMS analysis for food safety, including sugar syrups, additives, and honey authenticity verification. Our precise molecular profiling ensures product quality and authenticity, providing critical data for food safety assessment and industrial quality control.
Our forensic HRMS services support toxicological screening and mass spectrometry imaging. We detect drugs, poisons, and other bioactive substances in complex samples, offering high-confidence molecular insights for forensic investigations and toxicology research.
HRMS enables comprehensive studies in metabolomics, lipidomics, and proteomics. BOC Sciences supports high-throughput biomarker discovery and complex sample analysis, providing reliable and detailed molecular-level data for advanced omics research projects.
We analyze covalent protein–small molecule complexes with high precision, aiding drug target validation and mechanistic studies. Our HRMS testing delivers accurate molecular insights, supporting research and development in pharmaceutical and biochemical projects.
Our HRMS testing services provide tailored analytical strategies based on your sample characteristics and project requirements, ensuring reliable, reproducible results that support your R&D efforts and facilitate informed scientific decision-making.
Clients provide sample information and testing objectives. Our experts clarify goals and propose a customized HRMS testing plan.
Clients submit samples following guidance. The Laboratory performs preliminary checks and logs information for complete traceable sample management.
Our technical team designs a detailed HRMS analysis plan, including instrument setup, method selection, and data acquisition strategy.
Samples undergo HRMS analysis. Strict procedures and quality controls ensure accurate, reliable, and reproducible mass spectrometry data.
Professional analysts process and interpret HRMS data, providing clear results, molecular information, and visual charts for easy understanding.
A comprehensive report is prepared and delivered securely, including sample details, analysis conditions, results, and a summary for informed decision-making.
Clients can typically obtain detailed reports from our HRMS testing services:
We utilize high-resolution mass spectrometry to deliver precise molecular analysis with exceptional accuracy and sensitivity for complex samples.
Our team possesses extensive mass spectrometry experience, offering reliable data interpretation and scientifically robust testing solutions.
Analytical strategies are tailored to sample types and research goals, optimizing workflows and ensuring actionable, high-quality results.
We collaborate with leading universities and research institutions, leveraging advanced knowledge and technology to enhance solution innovation.
Client: A leading pharmaceutical company in North America
Challenge: The client needed accurate identification of unknown impurities in complex formulations, where conventional MS methods failed to deliver sufficient resolution or confidence in structural elucidation.
Solution: BOC Sciences applied high-resolution mass spectrometry combined with optimized chromatographic separation. Our team utilized advanced data acquisition strategies and in-house algorithms for precise mass determination and structural assignment of impurities. The workflow delivered clear impurity profiles with unambiguous molecular information.
Outcome: The client gained comprehensive insights into impurity characteristics, which enhanced their decision-making process in formulation optimization and supported internal quality assessment strategies.
Client: An innovative biotechnology company developing therapeutic proteins
Challenge: The client required detailed molecular characterization of a protein product, including assessment of structural heterogeneity and post-translational modifications, where standard analytical approaches lacked sufficient depth.
Solution: BOC Sciences performed intact mass analysis and peptide-level mapping using high-resolution Q-TOF instrumentation. Customized enzymatic digestion workflows, combined with bioinformatics-driven deconvolution, enabled complete identification of structural variants and modification patterns.
Outcome: The client obtained a clear molecular-level understanding of their protein candidate, which facilitated R&D advancement and supported confident scientific communication with collaborators and stakeholders.
Client: A contract research organization (CRO) focused on small molecule discovery
Challenge: The client faced challenges in characterizing complex metabolic profiles, especially in differentiating isobaric species and detecting minor metabolites.
Solution: BOC Sciences implemented UHPLC-HRMS with data-independent acquisition, integrating isotope-labeled standards and advanced fragmentation analysis. This approach enabled high-resolution detection, accurate mass filtering, and structural elucidation of both major and minor metabolites.
Outcome: The client achieved a complete and reliable metabolite map, which improved their research workflow efficiency and strengthened their service portfolio in early-stage studies.
HRMS provides superior resolution and mass accuracy, allowing precise differentiation of isotopes and isomers even in highly complex matrices. At BOC Sciences, we combine advanced HRMS platforms with an experienced technical team to deliver reliable molecular identification and structural elucidation, ensuring more comprehensive analytical outcomes.
HRMS Testing is widely applicable in impurity analysis for pharmaceuticals, biopharmaceutical characterization, metabolite identification, and natural product research. BOC Sciences tailors experimental workflows and analytical strategies to meet specific client needs, ensuring our services align with diverse R&D project requirements.
By offering high-accuracy mass measurement and detailed fragment ion analysis, HRMS Testing significantly improves data precision and traceability. BOC Sciences employs optimized sample preparation, advanced acquisition modes, and rigorous validation processes to guarantee results that are highly reliable for scientific and industrial applications.
Beyond state-of-the-art instrumentation, our strength lies in customizing analytical methods based on sample characteristics and molecular targets. BOC Sciences not only delivers qualitative data but also provides in-depth insights into structural features, modifications, and metabolic pathways—empowering clients to accelerate their research and development cycles.
Absolutely. Flexibility and applicability are at the core of our HRMS Testing services. BOC Sciences develops tailored solutions according to each client’s experimental objectives and sample properties. Whether analyzing a single molecule or a complex system, we deliver scientifically sound and actionable data that enable faster and more accurate project decisions.
The HRMS testing service from BOC Sciences provided detailed structural information that went far beyond conventional methods. Their advanced data interpretation and clear reporting gave our R&D team valuable insights into complex molecules.
— Dr. W., Head of Analytical Development, Global Pharmaceutical Company
We were impressed by the depth of expertise the BOC Sciences team demonstrated in HRMS analysis. From method optimization to data annotation, their approach was precise and highly professional, enabling us to strengthen our research outcomes with confidence.
— Prof. K., Principal Investigator, University Research Institute
BOC Sciences' HRMS testing services helped us resolve challenging questions about protein heterogeneity. Their ability to deliver accurate intact mass and modification data allowed us to advance our biologics program with solid analytical evidence.
— Dr. M., Senior Scientist, Innovative Biotech Company
The high-resolution metabolite profiling from BOC Sciences gave us a complete view of transformation pathways. Their customized workflows and efficient data analysis significantly improved the pace of our discovery projects.
— Dr. S., Project Manager, Contract Research Organization
