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GC-FTIR Testing

GC-FTIR Testing

BOC Sciences specializes in providing comprehensive Gas Chromatography-Fourier Transform Infrared (GC-FTIR) testing services, covering everything from complex sample analysis to in-depth molecular structure characterization. Utilizing advanced GC-FTIR technology, we deliver precise compound identification, detailed spectral analysis, and customized analytical solutions tailored to diverse sample types. Supported by a highly experienced scientific team and state-of-the-art instrumentation, BOC Sciences ensures reliable and efficient results that empower clients to obtain critical data for research, product development, and industrial applications. Our professional services have earned the trust and recognition of clients worldwide, demonstrating BOC Sciences' authoritative expertise in analytical chemistry.

What is GC-FTIR Testing?

GC-FTIR testing combines Gas Chromatography (GC) separation with Fourier Transform Infrared (FTIR) spectroscopy to provide both separation and molecular identification of compounds. In this technique, complex mixtures are first separated by GC based on volatility and chemical properties. Each component then passes through an FTIR detector, producing a unique infrared spectrum that reflects its molecular structure. This integration allows for precise identification of compounds, detection of subtle structural differences, and analysis of complex samples with high confidence, making GC-FTIR an essential tool in analytical chemistry and chemical research.

Complete GC-FTIR Services for Molecular Insight

Qualitative GC-FTIR Testing

Utilizes FTIR spectra to identify structural features of unknown compounds. This service enables precise determination of functional groups, bond types, and molecular structures. Experiments are optimized based on sample properties to provide reliable structural insights and support research and development projects.

Quantitative GC-FTIR Testing

Through peak integration or specific absorption bands, this service allows accurate calculation of component concentrations. Ideal for purity assessment and impurity profiling, our approach ensures reproducible quantitative data for complex organic mixtures.

Trace GC-FTIR Testing

By combining cryogenic trapping interfaces with high-sensitivity FTIR detection, trace-level compounds at ppb–ppm concentrations can be measured. This service is tailored for volatile and semi-volatile compounds, delivering highly sensitive and reliable data for low-abundance analytes.

Mixture GC-FTIR Testing

Designed for complex gas mixtures, this service separates individual components and provides structural identification using FTIR. Suitable for environmental air analysis, residual organic solvents, and other multi-component systems, our methodology ensures comprehensive mixture characterization.

Looking for Customized GC-FTIR Solutions?

Contact us to discuss your sample requirements, and we will recommend the optimal GC-FTIR approach to meet your analytical and research needs.

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Sample Types Supported by Our GC-FTIR Testing

MTT Assay

Sample Scope for GC-FTIR Testing

  • Volatile and semi-volatile organic compounds, e.g., hydrocarbons, esters.
  • Gaseous substances and volatile emissions from materials or packaging.
  • Trace component identification in complex mixtures.
  • Suitable for low-boiling, thermally stable compounds.
  • Provides structural information for unknown compound identification.
CCK-8 Assay

Basic Requirements for Samples

  • Sample form: liquid, gas, or solid soluble in common GC solvents.
  • Solvent should be high purity, e.g., HPLC or GC grade.
  • Concentration recommended between 0.1–10 mg/mL for accurate detection.
  • Sample volume: typically 0.5–2 mL for liquids, several mL for gases.
  • Provide chemical name, molecular formula, CAS number, and solvent info.

GC-FTIR Sample Submission – Request Form

Please provide the basic molecular information and your specific testing requirements in the submission form.

Submit Your Sample

GC-FTIR Multi-Detector Analytical Platform

Our GC-FTIR testing platform integrates advanced gas chromatography with Fourier Transform Infrared Spectroscopy, supporting a variety of detector combinations to enable precise structural characterization, quantitative analysis, and trace-level detection across complex samples. Key capabilities include:

Instrument TypeDetector CombinationKey Features
GC-FTIRFTIR onlyDirectly acquires IR spectra of separated components; suitable for structural identification; limited quantitative and trace-level sensitivity
GC-FTIR-MSFTIR + Mass Spectrometry (MS)FTIR provides functional group and bond information; MS provides molecular weight and fragmentation data to enhance qualitative analysis
GC-FTIR-FPD / GC-FTIR-NPDFTIR + FPD (Flame Photometric Detector) / NPD (Nitrogen-Phosphorus Detector)FTIR provides structural information; FPD/NPD improves sensitivity for sulfur, phosphorus, and nitrogen-containing compounds
GC-FTIR-FIDFTIR + FID (Flame Ionization Detector)FID enables high-sensitivity quantitative analysis of organic compounds; FTIR provides structural qualitative data
Multi-Detector GC-FTIRFTIR + MS + FID (or other combinations)Comprehensive data acquisition for structural identification, quantitative measurement, and trace detection

GC-FTIR Analysis Workflow by BOC Sciences

Requirement Understanding

1Initial Consultation and Sample Requirement Confirmation

Clients submit their testing needs via website or email. Our team reviews sample type, objectives, and provides professional guidance.

Experimental Design

2Sample Reception and Handling

Samples are securely received, labeled, and inspected. Proper storage and handling ensure integrity and accuracy of subsequent GC-FTIR analysis.

Model System Construction

3GC-FTIR Analysis Plan Design

A tailored GC-FTIR testing plan is created, including separation conditions, detection parameters, and data acquisition strategies for precise compound identification.

Pharmacological Testing Execution

4Sample Testing and Data Collection

Samples undergo GC-FTIR analysis under strict protocols. Chromatograms and infrared spectra are recorded to ensure reliable, reproducible data.

Data Collection and Analysis

5Data Analysis and Result Verification

Collected spectra are analyzed and compared to reference data. Each result undergoes quality checks for accuracy and clear identification.

Report Delivery

6Report Preparation and Delivery

A detailed professional report is generated, including spectra, compound identification, and technical notes, delivered electronically for client use.

Contact Us to Quickly Start Your GC-FTIR Testing Services

BOC Sciences' GC-FTIR testing services provide precise gas chromatographic separation coupled with Fourier-transform infrared analysis, delivering accurate molecular identification and structural characterization to support efficient progress in research, development, and analytical projects.

Request a Quote

Comprehensive GC-FTIR Analysis Reports

Sample Information

  • Sample ID and batch number recorded accurately
  • Sample description: liquid, solid, or mixture
  • Pre-treatment method: dilution or purification applied
  • Instrument and method conditions clearly specified

Analytical Results

  • GC chromatogram showing retention times clearly
  • FTIR spectra corresponding to GC peaks recorded
  • Component identification based on spectral library match
  • Relative content or peak area percentages provided

Interpretation and Conclusion

  • Main components and impurities summarized effectively
  • Functional groups confirmed via characteristic IR peaks
  • Unknown components structurally inferred if possible
  • Overall composition and recommendations briefly stated

Advantages of BOC Sciences GC-FTIR Testing

High-Sensitivity Analytical Capability

Our advanced GC-FTIR systems enable precise identification of volatile and semi-volatile compounds, capturing trace-level components with enhanced signal-to-noise performance.

Extensive Spectral Libraries and Expertise

Leveraging thousands of FTIR spectra and proprietary algorithms, we provide confident identification of unknown components within complex mixtures for advanced research applications.

Tailored Separation and Detection Strategies

We customize GC conditions and IR detection parameters based on sample characteristics, optimizing chromatographic resolution while minimizing co-elution interference.

Comprehensive Data Analysis and Structural Elucidation

Beyond standard spectra, we deliver functional group analysis and molecular structure interpretation, providing high-value insights for scientific research and material characterization.

Applications Supported by GC-FTIR Testing

With BOC Sciences' GC-FTIR applications, your projects gain reliable support in impurity identification, stability monitoring, and quality control.

Chemical & Materials Industry

Food & Consumer Products Industry

GC-FTIR Testing Case Studies and Success Stories

Client: Global pharmaceutical R&D company

Challenge: The client needed precise identification of trace organic impurities in early-stage small molecule drug candidates, where conventional techniques could not resolve structural isomers in complex reaction mixtures.

Solution: BOC Sciences applied GC-FTIR with high-resolution capillary columns and optimized temperature gradients. Our team combined spectral deconvolution with tailored FTIR detection to differentiate closely related molecular structures, providing detailed chromatograms and structural reports.

Outcome: The client obtained clear identification of trace impurities and isomers, enabling more informed synthetic route optimization and accelerated compound development.

Client: Biopharmaceutical company developing novel CNS therapeutics

Challenge: The client required rapid identification of volatile and semi-volatile drug metabolites in complex assay mixtures, where overlapping peaks hindered conventional analysis.

Solution: BOC Sciences implemented GC-FTIR with customized column chemistry and split injection techniques, achieving high separation efficiency. FTIR spectral matching and deconvolution provided structural elucidation of metabolites without sample derivatization.

Outcome: The client obtained comprehensive metabolite profiles, supporting lead optimization and early-stage ADME studies with confidence in structural assignments.

Client: Mid-size pharmaceutical manufacturer

Challenge: The client needed detailed structural analysis of volatile by-products and impurities generated during API synthesis, to guide process optimization and improve reaction selectivity.

Solution: BOC Sciences deployed GC-FTIR with selective sampling techniques and advanced FTIR detection, providing precise identification of minor components even in complex reaction mixtures. Customized spectral libraries and quantitative analysis allowed for rapid comparison across process batches.

Outcome: The client streamlined process development by accurately identifying minor by-products, enabling improved yield, reproducibility, and efficient scale-up strategies.

Frequently Asked Questions

Client Reviews: GC-FTIR Testing Services

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