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DSC Testing

DSC Testing

At BOC Sciences, we provide a full spectrum of DSC testing services, designed to meet the diverse analytical needs of industries ranging from pharmaceuticals and polymers to chemicals and materials science. Our capabilities cover precise thermal property analysis, formulation assessment, and material characterization, supported by advanced instrumentation and experienced scientists. Clients consistently highlight our accuracy, professional communication, and timely insights, making us a trusted partner for reliable DSC testing solutions that help optimize material performance and inform research and development decisions.

What is Differential Scanning Calorimetry (DSC)?

DSC is a thermoanalytical technique used to measure the heat flow associated with material transitions as a function of temperature or time. By monitoring endothermic and exothermic events, DSC provides insights into melting points, crystallization behavior, glass transitions, and thermal stability. The technique is highly sensitive, allowing for the detection of subtle thermal changes in complex formulations. DSC testing is widely applied in material characterization, product development, and quality control, enabling scientists to understand physical and chemical properties critical for product optimization and innovation.

Comprehensive DSC Testing Services at BOC Sciences

Melting Temperature and Enthalpy (Tm, ΔHm)

Our DSC testing determines the melting point and purity of polymers, pharmaceuticals, and metal alloys. By capturing clear endothermic transitions, we provide precise thermal profiles to assess material homogeneity, melting behavior, and support product development.

Crystallization Temperature and Enthalpy (Tc, ΔHc)

Using controlled cooling scans, we assess polymer crystallization behavior. This analysis evaluates crystallization kinetics, thermal response, and structural characteristics, delivering insights that help optimize processing conditions, improve mechanical performance, and enhance thermal stability.

Glass Transition Temperature (Tg)

Stepwise heat capacity analysis identifies "brittle-to-tough" transitions in polymers, foods, and related materials. Reliable Tg data from our DSC testing supports prediction of thermal behavior, guides formulation improvements, and ensures consistent material performance.

Curing and Crosslinking Analysis

Isothermal and dynamic DSC studies quantify curing efficiency and crosslinking degree in resins, adhesives, and coatings. These measurements provide critical insights for formulation optimization, process development, and improved performance of thermosetting materials.

Oxidation Induction Time/Temperature (OIT)

Thermal-oxidative resistance of polymers is evaluated through controlled oxygen exposure. Our DSC measurements allow precise assessment of oxidative stability, assisting material selection and supporting the development of durable, high-performance polymer products.

Heat Capacity (Cp)

Specific heat capacity across 25–300 ℃ is measured using standard or modulated DSC techniques. This data supports thermal management, process simulation, material design, and engineering decisions, providing accurate insights into material performance.

Degree of Crystallinity (%)

Crystallinity is calculated using reference enthalpy values, offering quantitative insight into polymer structure and morphology. Our DSC testing informs processing optimization, enhances mechanical and thermal properties, and enables precise material characterization.

Cold Crystallization and Multiple Melting Behavior

Re-crystallization and dual melting peaks in semi-crystalline polymers such as PET and PLA are studied to reveal thermal history effects. DSC analysis provides insights into crystallization behavior and processing parameters, guiding material performance predictions.

Phase Transitions and Curie Temperature

Solid-state phase transitions and Curie temperatures are measured for metals, alloys, and magnetic materials. DSC testing provides essential data for advanced material design, performance assessment, and optimization of thermal and magnetic properties.

Need Detailed Thermal Analysis?

Tell us about your material and testing needs, and our experts will suggest the most suitable DSC methods for accurate thermal characterization.

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Sample Types Supported by Our DSC Testing

MTT Assay

Supported Sample Types

  • Polymers and Macromolecules: Includes plastics, elastomers, thermosetting resins, and semi-crystalline polymers such as PET and PLA.
  • Metals and Alloys: Includes metal solders, light alloys, functional alloys, and magnetic materials.
  • Food and Natural Products: Includes carbohydrates, lipids, proteins, and composite food matrices.
  • Pharmaceuticals and Chemicals: Includes small-molecule drugs, solid reagents, and crystalline compounds.
CCK-8 Assay

Sample Requirements

  • Physical State: Must be compatible with DSC sample pans or specialized containers; liquids require sealed pans to prevent evaporation.
  • Sample Quantity: Typically 5–20 mg, depending on material type and testing method.
  • Homogeneity: Samples should be well-mixed or ground to ensure accurate thermal signal detection.
  • Thermal Stability: Samples should remain stable in the DSC testing temperature range; decomposition-prone materials require controlled heating or an inert atmosphere.

DSC Testing – Sample Submission Form

Samples for DSC testing can be submitted using our Sample Submission Form. Our team will provide guidance on sample preparation and recommend the most suitable DSC testing methods.

Submit Your Sample

Advanced Atmosphere-Controlled DSC Testing Platform

Our DSC service platform is equipped with state-of-the-art instruments and versatile testing capabilities, allowing precise thermal analysis under controlled atmospheres for both research and industrial applications. Key capabilities include:

Atmosphere / EnvironmentApplication
N2 (Inert)Prevent oxidation during thermal analysis, suitable for oxygen-sensitive samples.
Air / O2Induce oxidation, evaluate thermal oxidative stability of materials.
Dry Ar / HeEnable low-temperature measurements or applications requiring high thermal conductivity.
Humidity-Controlled (RH-DSC)Study hydrates, protein denaturation, and moisture-sensitive phenomena.

BOC Sciences DSC Testing Workflow

Requirement Understanding

1Initial Consultation and Requirement Assessment

Clients contact us via email, phone, or form, describing sample type and testing goals. Our team provides tailored DSC testing recommendations.

Experimental Design

2Sample Preparation and Submission

Clients prepare samples following our guidelines. Proper packaging and handling ensure safe delivery and integrity of the samples for testing.

Model System Construction

3Test Plan Design and Confirmation

Our team designs DSC test parameters, including temperature range and scan rate. Clients review and approve the plan before testing begins.

Pharmacological Testing Execution

4DSC Testing Execution

Expert technicians perform DSC measurements under controlled conditions. Real-time monitoring ensures precise, reliable data throughout the experiment.

Data Collection and Analysis

5Data Analysis and Result Compilation

Thermal data is professionally analyzed. Clear graphs and parameters are generated, providing comprehensive understanding of sample thermal behavior.

Report Delivery

6Report Delivery and Technical Support

Clients receive a detailed DSC test report. Our team offers consultation to interpret results and advise on further experimental considerations.

Start Your DSC Testing with Precision and Speed

Our DSC testing solutions provide detailed thermal characterization of polymers, pharmaceuticals, and other materials, supporting informed decisions in R&D and quality control.

Request a Quote

DSC Thermal Properties Evaluation Report

BOC Sciences provides DSC testing to generate thermal data for client applications as follows.

Basic Information and Test Conditions

  • Sample information: name, ID, batch number, purity
  • Instrument information: model, serial number, calibration status
  • Test conditions: temperature range, heating/cooling rate, atmosphere type
  • Sample preparation method and sample amount

Measurement Data and Heat Flow Curves

  • Raw heat flow curves (Temperature vs. Heat Flow)
  • Thermal transitions include Tg, Tc, Tm, and Td (if high-temperature scan)
  • Peak data table (Onset Temperature, Peak Temperature, Endset Temperature, ΔH)
  • Quantitative analysis (e.g., crystallinity, composition ratios in multi-phase systems)

Analysis Results and Conclusions

  • Interpretation of thermal transitions
  • Assessment of sample thermal stability, processability, or performance
  • Comparison with reference standards or historical data
  • Conclusive remarks and recommendations

Why Choose BOC Sciences for DSC Analysis?

01

Advanced Instrumentation

BOC Sciences utilizes state-of-the-art DSC instruments with ±0.01 ℃ temperature precision and enhanced heat flow sensitivity, enabling accurate characterization of diverse small and macromolecular samples.

02

Experienced Scientific Team

Our experts possess extensive thermal analysis experience, capable of optimizing DSC testing conditions for varied sample types, delivering highly reliable and insightful thermal property interpretations.

03

Strong Collaborative Network

BOC Sciences partners with leading instrument manufacturers and research institutions, providing technical support for complex samples and enabling interdisciplinary solutions for specialized thermal analysis.

04

Customized Data Analysis and Reporting

We deliver not only high-quality raw thermal data but also tailored insights into glass transitions, melting behavior, and phase changes, supporting informed research and process decisions.

Key Applications Supported by DSC Testing

BOC Sciences provides DSC testing services that can be applied across multiple fields, helping you address diverse research and development needs.

Drug & Formulation Development

  • Excipient Compatibility Assessment
  • Formulation Stability Evaluation
  • API Thermal Profiling

Chemical Synthesis & Materials Research

  • Scale-up Feasibility Testing
  • Material Thermal Characterization
  • Crystallization Process Monitoring

Product Quality & Performance Evaluation

  • Glass Transition and Melting Analysis

DSC Testing Case Studies and Success Stories

Client: A leading European polymer manufacturer

Challenge: The client required accurate characterization of glass transition, melting, and crystallization behavior in novel polymer blends to optimize mechanical and thermal properties.

Solution: BOC Sciences employed high-sensitivity DSC instruments with precise temperature control and calibrated heating/cooling rates. Our team conducted stepwise thermal scans, analyzed endothermic and exothermic events, and provided detailed thermograms with quantitative transition temperatures and enthalpy values.

Outcome: The client obtained precise thermal profiles, enabling rational selection of polymer compositions and improved processing strategies, which enhanced material performance consistency.

Client: A multinational specialty chemicals company

Challenge: The client needed to assess thermal interactions and potential incompatibilities between multiple excipients in solid formulations to ensure stability during processing.

Solution: BOC Sciences applied DSC testing with controlled heating cycles and modulated DSC techniques. Our team interpreted thermal events, including overlapping transitions and interaction peaks, providing quantitative enthalpy changes and onset temperatures to evaluate compatibility.

Outcome: The client achieved a clear understanding of excipient interactions, allowing informed selection of formulation components and optimization of manufacturing conditions.

Client: An advanced materials research institute in Asia

Challenge: The client required a detailed analysis of crystallization behavior and thermal stability of high-performance composites under varying thermal cycles.

Solution: BOC Sciences utilized high-resolution DSC with isothermal and non-isothermal scanning protocols. Our experts extracted crystallization temperatures, kinetic parameters, and melting behavior, providing comprehensive insights into thermal transitions and material stability.

Outcome: The client gained robust data on thermal behavior and crystallization kinetics, supporting rational material design and improved reliability in high-temperature applications.

Frequently Asked Questions

Client Reviews: DSC Testing Services

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