Dissolution testing is a fundamental analytical technique used to evaluate how active pharmaceutical ingredients are released from dosage forms such as tablets or capsules into a liquid medium. This process provides critical insights into formulation performance and product consistency. At BOC Sciences, we deliver comprehensive dissolution testing services covering routine QC, biorelevant, and modified-release evaluations. Equipped with advanced analytical platforms and a highly experienced scientific team, we ensure precise, reproducible results that accelerate formulation optimization and R&D efficiency. Our global clients, ranging from pharmaceutical innovators to formulation developers, trust BOC Sciences for reliable, data-driven dissolution testing solutions.
At BOC Sciences, we provide tailored dissolution testing solutions to precisely measure drug release profiles from tablets and capsules. By optimizing experimental conditions, we deliver high-quality data to support formulation improvement, dosage performance enhancement, and informed R&D decision-making.
BOC Sciences conducts multi-media and multi-stage dissolution testing to simulate drug release under different pH conditions in the gastrointestinal tract. This service supports pH-sensitive or enteric formulations and provides data for complex dosage form optimization.
For sustained or controlled-release formulations, we perform modified release dissolution testing to track drug release kinetics. BOC Sciences' precise experimental design helps clients improve dosage performance, optimize formulations, and accelerate R&D progress.
BOC Sciences offers biorelevant dissolution testing using simulated physiological fluids to evaluate drug release behavior. The data help R&D teams predict in vivo performance, guide formulation optimization, and enhance decision-making reliability during development.
Offering diverse dissolution testing solutions for multiple sample types, BOC Sciences delivers expert support tailored to your project needs.
Provide your samples or product information, and we'll offer free expert guidance and customized testing solutions.
At BOC Sciences, our dissolution testing platform integrates advanced analytical technologies and a skilled scientific team, ensuring high-quality, precise, and reproducible results across diverse formulation studies. To accurately measure drug release from these dissolution tests, we utilize advanced analytical instruments as follows:
BOC Sciences delivers a full suite of dissolution testing equipment to meet diverse dosage form needs:
| Instrument Type | Instrument Name | Application Description |
| Type I | Basket Apparatus | Designed for tablets and floating or fragile capsules; the dosage form is placed in a rotating basket to facilitate dissolution. |
| Type II | Paddle Apparatus | Widely applicable for most tablets and capsules; the paddle ensures uniform stirring and consistent dissolution. |
| Type III | Reciprocating Cylinder / Flow-Through Cell | Optimized for sustained or controlled-release formulations; circulating medium simulates dynamic dissolution conditions. |
| Type IV | Flow-Through Cell Apparatus | Provides precise control over drug release rates; suitable for low-solubility or specialized formulations. |
| Type V | Paddle Over Disk | Ideal for films or coated tablets; the dosage form is fixed on a disk while the paddle stirs the medium. |
| Type VI | Rotating Cylinder | Tailored for lipid-based or sustained-release formulations requiring specialized dissolution testing. |
| Type VII | Hybrid Flow-Through / Reciprocating Holder | Supports complex or innovative dosage forms, enabling simulation of multiple release mechanisms. |
Clients share formulation details and testing goals. Our experts define objectives and design an appropriate testing plan.
We create customized dissolution protocols, choosing optimal apparatus, media, and parameters for reliable, reproducible results.
Testing is conducted under controlled conditions using advanced instruments to ensure reliable data acquisition.
Results are analyzed and summarized. Clients receive detailed reports supporting formulation development decisions.
BOC Sciences provides dissolution testing solutions supporting formulation design. Our advanced analytical capability enables accurate evaluation of release profiles, helping drug developers predict in vivo performance and refine dosage forms for enhanced bioavailability.
We offer dissolution testing solutions that assist formulation scientists in assessing excipient impact, release kinetics, and stability. Our platform delivers high-precision data to guide formulation adjustments, ensuring consistent performance and product robustness.
BOC Sciences provides dissolution testing solutions for consistent product quality evaluation. We help manufacturing and QC teams establish dissolution specifications, assess batch uniformity, and ensure product consistency through reliable and repeatable testing protocols.
For R&D teams developing novel drug delivery systems, BOC Sciences offers specialized dissolution testing solutions enabling precise characterization of release behavior under diverse conditions. Our accurate data support formulation screening and early-stage innovation.
Contact BOC Sciences to initiate your dissolution testing services. Our team provides precise, high-resolution release profiles for a wide range of dosage forms, enabling informed formulation optimization and accelerating your research and development projects efficiently.
Our dissolution testing reports provide detailed release profiles, quantitative data, and trend analysis, varying by specific test requirements.
We use advanced analytical instruments to deliver precise, sensitive dissolution data for a wide range of formulations.
Supporting 20+ dosage forms, our platform covers tablets, capsules, and controlled-release systems.
Streamlined workflows and automated sampling enable efficient testing while maintaining reproducible, high-quality results for all samples.
Our scientists provide detailed analysis, interpretation of release profiles, and actionable insights supporting formulation development.
Client Needs: A pharmaceutical company developing immediate-release small-molecule tablets required precise dissolution testing to ensure consistent drug release and support formulation optimization.
Challenges: The client observed significant batch-to-batch variability in in vitro dissolution profiles, making it difficult to predict systemic absorption and select optimal formulations efficiently.
Solution: BOC Sciences implemented a tailored dissolution testing workflow using USP-compliant apparatus with optimized sampling intervals. Automated data collection and analysis allowed for high-resolution profiling across multiple batches.
Outcome: Provided reliable dissolution profiles that identified variability sources and enabled the client to optimize excipients and manufacturing parameters. This accelerated formulation selection and ensured reproducible in vitro performance.
Client Needs: A pharmaceutical company developing extended-release (ER) capsule formulations required detailed dissolution evaluation to compare release kinetics and guide prototype selection.
Challenges: The client faced inconsistent drug release due to matrix composition differences, and traditional sampling intervals failed to capture subtle kinetic variations, complicating formulation ranking.
Solution: BOC Sciences conducted high-resolution dissolution testing with multi-point sampling and kinetic modeling. Customized dissolution media reflected physiological conditions to accurately simulate release profiles.
Outcome: Delivered detailed dissolution kinetics for all prototypes, allowing the client to identify optimal ER formulations, streamline prototype selection, and reduce development iteration cycles.
Client Needs: A pharmaceutical company developing combination tablets containing multiple active ingredients required dissolution testing to evaluate simultaneous release profiles and support formulation design.
Challenges: The client struggled with interference between actives, resulting in inconsistent dissolution readings and difficulty in predicting in vivo performance for each component.
Solution: BOC Sciences implemented a multi-analyte dissolution testing strategy with optimized sample separation and HPLC quantification, ensuring accurate, component-specific release profiles.
Outcome: Provided clear, reproducible dissolution profiles for each active ingredient. The client could confidently refine formulations, ensuring balanced release and enhancing overall product quality.
A dissolution test evaluates the release rate and pattern of drugs from solid or liquid formulations. By simulating in vitro conditions, it provides insights into how the drug may behave in vivo. BOC Sciences offers a complete dissolution testing platform for tablets, capsules, and controlled-release formulations, supporting R&D and formulation optimization with high-precision analysis.
Dissolution testing of suspensions requires careful consideration of particle size, dispersion, and stability. BOC Sciences selects appropriate apparatus and dissolution media, applying precise agitation and real-time sampling to generate comprehensive release profiles. This enables clients to evaluate formulation performance and optimize suspension characteristics effectively.
A typical dissolution test procedure includes sample preparation, selection of apparatus and media, execution of the test, and data analysis. BOC Sciences provides end-to-end services, from initial consultation to report delivery, ensuring precise operation at every step and delivering reliable quantitative and trend analyses.
For innovative formulations, dissolution testing simulates varied physiological environments to assess the performance of new delivery systems. BOC Sciences applies multiple apparatus types and high-precision analytical instruments to generate detailed release profiles and comprehensive reports, helping clients optimize formulation design and development strategy.
With versatile instrumentation, multi-dosage form capability, and an experienced scientific team, BOC Sciences delivers precise data, multi-condition testing, and in-depth interpretation. Our services support clients in refining R&D strategies and making informed, efficient, and reliable decisions.
The dissolution testing service from BOC Sciences consistently produces precise and reproducible release profiles. Their expert team tailored testing methods to our complex formulations, providing insights that were critical for formulation optimization. This reliability has greatly supported our R&D decision-making.
— Dr. H., Senior Scientist, Pharmaceutical R&D Company
BOC Sciences provided comprehensive dissolution testing solutions, including method design and multi-condition analysis. Their attention to detail and systematic data reporting allowed us to fully understand the performance of our tablets and capsules, enabling informed development strategies.
— Dr. M., Formulation Scientist, Mid-sized Biotech Company
Using advanced analytical instruments, BOC Sciences delivered high-resolution dissolution data that clearly characterized our novel dosage forms. Their professional analysis and interpretive reports helped our team make confident decisions in early-stage formulation screening.
— Dr. S., R&D Project Lead, Innovative Drug Delivery Company
BOC Sciences' dissolution testing team provided not only accurate data but also actionable insights and guidance. Their experience with various dosage forms and controlled-release systems made the process smooth and informative, directly supporting our formulation refinement efforts.
— Dr. Y., Senior Formulation Scientist, Pharmaceutical Development Group
