Nanoparticle Conjugation Services
Nano-biological conjugated technology brings hope for the treatment of gliomas and other neurodegenerative diseases. Glioma is the deadliest type of cancer, and the options for treatment are very limited. In December 2010, scientists in the United States and Germany developed a multifunctional Nano-biological conjugated technology, which provided the ability to transport antisense oligodeoxynucleotides (AONs) across the blood-brain barrier (BBB) and the blood-brain tumor barrier (BTB), and targeted their payloads at tumors for receptor-regulated cell uptake, intracellular escape and release into the cytoplasm. Using this technique, the researchers demonstrated an inhibitory effect on the growth of intracranial tumors in a xenograft mouse model of human glioma.
Application of Nanoparticle Conjugation
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Agglutination Tests and Assays
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Particle capture ELISA
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Lateral flow tests
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Solid phase assays
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Scintillation proximity assays
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Polymerase chain reaction (PCR) tests
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Superparamagnetic-based assays
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Magnetic separation systems
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Calibration/Validation
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Cell Separation
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Flow Cytometry/Fluorescence Microscopy
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Immunochromatographic Strip Tests/Assays
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Instrument QC
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Molecular Diagnostics
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Nucleic Acid Purification
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Protein Purification
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Proximity Assays
Our Services
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Our custom conjugated formula service can either serve as a follow-up service, from our microoptimization service, to provide you with mass customization of antibody-nanoparticles couplers, or as a separate bonding service to provide you with the professional couplers of your choice.
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Our internal team of expert conjugate scientists will quickly generate your couplets at the optical density of your choice in the buffer of your choice.
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Alternatively, we can provide a complete purification service before binding, or purchase commercially available antibodies on your behalf.
Our Advantages
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A coupling compound of high quality and excellent performance.
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State-of-the art chemical biology facilities
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Flexible service choice.
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Experience and ability of dedicated team.
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Manufacturing technology transfer
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The agreed conjugate rate and scale.
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Evidence of successful bonding is provided.
Relying on state-of-the-art chemical and biological facilities and more than 30 years of comprehensive experience in providing high-quality bio-conjugated complexes, BOC Sciences’s customized nanoparticle conjugation service is flexible, repeatable and quality guaranteed! If you are interested in the services we can provide and would like more detailed information, please feel free to contact us and get exclusive technical support services. Our project manager will contact you as soon as possible and help you design appropriate agreements to meet your specific requirements.
Advance nanotechnology with BOC Sciences nanoparticle conjugation services
We deliver nanoparticle conjugation services with precise surface modifications to meet advanced research and diagnostic needs.
Submit your inquiry to request a custom solution.
References
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Wen, Y., McLaughlin, C. K., Lo, P. K., Yang, H., & Sleiman, H. F. (2010). Stable gold nanoparticle conjugation to internal DNA positions: facile generation of discrete gold nanoparticle-DNA assemblies. Bioconjugate chemistry, 21(8), 1413-1416.
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Azab MM, Cherif R, Finnie AL, El-Alamin MM, Sultan MA, Wark AW. Optimized polydopamine coating and DNA conjugation onto gold nanorods for single nanoparticle bioaffinity measurements. Analyst. 2018; 143(7):1635-43.
If you have questions about our services at any time, just give us a call or send us an email at . We will do all we can to meet your needs.
Our Highlights
- Advanced computer aided technology
- Custom synthesis for small molecules
- One-stop, systematic services
- Experienced technical team
- Technical support, quality assurance
