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GC-IR Testing

GC-IR Testing

Our GC-IR testing services cover the full spectrum of analytical needs for chemical, biochemical, and industrial applications. Utilizing advanced gas chromatography coupled with infrared spectroscopy, BOC Sciences provides precise qualitative and quantitative analysis of complex samples. Our team of experienced scientists ensures accurate, reproducible results, while maintaining strict attention to data integrity and confidentiality. Clients consistently recognize our technical expertise, thorough reporting, and responsive support. From routine testing to specialized analytical solutions, BOC Sciences' GC-IR services deliver actionable insights that help optimize research, development, and production processes across diverse industries.

What is GC-IR Testing?

GC-IR testing, or Gas Chromatography–Infrared Spectroscopy, is an advanced analytical technique that integrates the separation power of gas chromatography with the molecular specificity of infrared spectroscopy. In this process, volatile and semi-volatile sample components are first vaporized and carried through a GC column by an inert gas, where they are separated based on differences in volatility, polarity, and interaction with the stationary phase. Each resolved compound then passes into an infrared spectrometer, where it absorbs characteristic wavelengths of IR radiation, generating a unique molecular fingerprint. This combination allows simultaneous separation, identification, and structural characterization of complex mixtures with high specificity and accuracy.

Comprehensive GC‑IR Detection Services from BOC Sciences

GC-vpIR (Vapor Phase IR)

We provide GC-vpIR services, directing GC-separated components straight into an infrared detector for rapid, real-time analysis. This method requires minimal sample preparation and is ideal for volatile organic compounds, fragrances, and environmental air monitoring, delivering reliable qualitative structural insights for our clients.

GC-sdIR (Solid Deposition IR)

We offer GC-sdIR testing, depositing separated components onto a cooled surface as a solid for infrared measurement. This approach suits high-boiling or low-volatility compounds, providing stable spectra and precise identification of chemical intermediates, specialty chemicals, and challenging analytes in complex mixtures.

GC-liquid IR (Liquid IR)

We provide GC-liquid IR services, condensing or dissolving GC-separated fractions for subsequent infrared analysis. This technique supports high-boiling liquids and organic solvents, enabling clear functional group characterization and structural analysis for samples unsuitable for direct gas-phase detection.

GC-off-line IR (Offline GC-IR)

We conduct GC-off-line IR testing, collecting separated fractions for infrared measurement, allowing flexible sample handling and high-sensitivity analysis. This method is particularly effective for trace components and complex mixtures, providing accurate structural elucidation and robust support for research and development.

Need Expert GC-IR Analysis?

Share your sample information, and our team will suggest the best GC-IR testing approach.

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Accepted Sample Categories for GC-IR Testing

MTT Assay

Sample Scope

  • Volatile Organic Compounds: Solvents, essential oils, fragrances, and air samples.
  • Low-to-Medium Molecular Weight Organics: Oils, fuels, and liquid chemical compounds.
  • Complex Mixtures: Chemical intermediates or unknown mixtures requiring separation.
  • Gas Samples: Gas mixtures analysis for component identification and quantification.
CCK-8 Assay

Basic Requirements for Samples

  • Sample Quantity and Purity: 1–5 mL liquid or 1–10 mg solid/powder recommended.
  • Solvent Compatibility: Use GC-compatible solvents, avoid high boiling or strong polarity.
  • Container Requirements: Sealed, chemically resistant bottles to prevent evaporation or degradation.
  • Labeling and Information: Include sample name, batch number, concentration, and hazards.

GC-IR Analysis – Sample Submission Form

Provide your sample details, and our team will ensure optimal GC-IR testing.

Submit Your Sample

Advanced GC-IR Coupling and Detection Platforms

Our GC-IR platform at BOC Sciences offers a comprehensive range of advanced coupling techniques, enabling detailed structural and isotopic analysis across complex samples. These services integrate infrared spectroscopy with mass spectrometry, pyrolysis, and isotope ratio analysis, supporting precise identification, differentiation of isomers, and specialized research applications. Key GC-IR capabilities include:

TechnologyPrinciple / FeaturesApplications
GC-IRMSGC-separated components are analyzed for isotopic ratios using mass spectrometry.Isotope composition determination, source tracing, environmental and food safety studies.
GC-IR + MSInfrared spectra and mass spectral data are acquired simultaneously, enhancing structural elucidation.Precise structural identification, differentiation of isomers.
GC-MS-IRGC-MS provides molecular weight and fragment information while IR delivers functional group analysis.Highly complex samples, forensic, and chemical analysis.
GC-Py-IRPolymers or low-volatility samples are pyrolyzed, separated by GC, and analyzed by IR.Polymer characterization, materials chemistry research.

Step-by-Step GC-IR Analysis Service Process

Requirement Understanding

1Consultation and Requirement Assessment

Clients submit sample information and analysis needs. Our technical team evaluates and provides professional guidance for accurate testing solutions.

Experimental Design

Sample Submission and Preparation Guidance

Clients send samples to BOC Sciences. Experts advise on proper preparation, solvent selection, and concentration to ensure reliable GC-IR analysis.

Model System Construction

Method Development and Instrumental Analysis

Our specialists develop optimized GC-IR methods, combining high-resolution chromatography and infrared spectroscopy to identify complex sample components.

Pharmacological Testing Execution

Data Processing and Structural Interpretation

Collected GC-IR data undergo peak identification, spectral matching, and structure confirmation, ensuring scientifically accurate and interpretable results.

Data Collection and Analysis

Report Compilation and Expert Review

A professional report is prepared, detailing component analysis, structural confirmation, and method explanation, reviewed by experienced analysts.

Report Delivery

Report Delivery and Ongoing Support

Reports are securely delivered to clients. Our team provides follow-up support for result interpretation and further analytical guidance.

Start Your GC-IR Testing Projects Today

BOC Sciences offers comprehensive GC-IR testing services that combine gas chromatography with infrared detection, providing precise structural elucidation and molecular analysis to help researchers and developers advance their projects efficiently.

Request a Quote

Analytical Reports Provided by BOC Sciences

Sample and Test Information

  • Sample name, batch number, and source provided
  • Test report number and laboratory identification
  • Analysis date, completion date, and personnel
  • Sample preparation and storage conditions documented

Analytical Results

  • Target compounds identified by retention time
  • IR spectral features matched to structures
  • Component content expressed in percentage
  • Chromatograms and spectra included for review

Result Interpretation

  • Purity assessment compared to expected values
  • Notes on unusual or unknown peaks
  • Quantitative method performance briefly reported
  • Recommendations for further analysis, if needed

Why Choose BOC Sciences for GC-IR Analysis?

Advanced Instrumentation for High-Precision Analysis

BOC Sciences utilizes high-resolution GC-IR systems, capable of detecting trace components at ppb levels, ensuring accurate analysis of complex sample structures.

Experienced Expert Team

Our analytical team possesses extensive GC-IR expertise, handling diverse sample types with tailored methods for reliable interpretation and scientifically valuable insights.

Extensive Partner Network

We maintain a global network of laboratories and suppliers, providing optimal resources and collaboration to ensure feasibility and flexibility for challenging or rare samples.

In-Depth Data Analysis and Value-Added Reports

Beyond basic spectra, we offer customized interpretation and trend analysis, leveraging extensive spectral databases to deliver actionable insights for R&D and quality studies.

Applications Supported by Our GC-IR Testing

BOC Sciences provides GC-IR Testing services that support a broad spectrum of applications in pharmaceutical research and development.

Drug Discovery

  • Drug molecule structure analysis
  • Drug impurity testing
  • API Analysis
  • New drug process optimization

Drug Quality Control

  • API quality control
  • Intermediate analysis
  • Finished drug consistency testing
  • Material stability study

Formulation & Excipients Development

  • Excipient compatibility analysis
  • Solid dosage component analysis
  • Solution formulation component testing
  • Formulation process optimization

GC-IR Testing Case Studies and Success Stories

Client: A leading flavor and fragrance manufacturer in Europe

Challenge: The client required precise separation and identification of volatile and semi-volatile compounds in complex essential oil and fragrance mixtures, where conventional analysis often caused overlapping peaks and ambiguous results.

Solution: BOC Sciences implemented advanced GC-IR, optimizing column selection and temperature programming for targeted separation. Our team applied tailored sample introduction techniques and high-sensitivity IR detection to generate detailed spectral fingerprints for each compound.

Outcome: The client obtained highly resolved chromatograms and accurate structural identification of key aroma constituents, significantly improving formulation precision and product consistency.

Client: A major petrochemical company in North America

Challenge: The client needed robust identification of complex hydrocarbon mixtures with overlapping molecular structures, ensuring accurate characterization of unknown or minor components.

Solution: BOC Sciences utilized GC-IR with high-resolution capillary columns and optimized split/splitless injection methods. Advanced infrared spectral deconvolution and integration with chromatographic data allowed precise differentiation of structurally similar hydrocarbons.

Outcome: The client achieved enhanced compound discrimination, reliable quantification of trace components, and comprehensive analytical reports that supported R&D and process optimization projects.

Client: An environmental testing laboratory in Asia

Challenge: The client required sensitive and selective analysis of trace volatile organic compounds (VOCs) in air and water samples, where complex matrices often interfered with detection.

Solution: BOC Sciences applied GC-IR with tailored stationary phases and temperature gradients, combined with high-sensitivity infrared detectors. Our team optimized sample pre-concentration and matrix removal techniques, enabling clear separation and spectral identification of VOCs at low concentrations.

Outcome: The client obtained accurate identification of environmental contaminants, improved analytical resolution, and high-quality, interpretable reports that enhanced decision-making for environmental monitoring projects.

Frequently Asked Questions

Client Reviews: GC-IR Testing Services

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