Computer-aided drug design (CADD) is a widely used technology using computational tools and resources for the storage, management, analysis and modeling of compounds. It relies on digital repositories for the study of designing compounds with physicochemical characteristics, predicting whether a given molecule will be combined with the target, and if so how strongly. Computer-based methods can help us to search new hits in drug discovery, screening many irrelevant compounds at the same time and study the structure-activity relationship of drug molecules.LEARN MORE
Lead optimization is a diversified operation in drug discovery, in which the chemical structures of compounds or biologics are modified to improve target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties to generate preclinical drug candidates. In order to understand the need for lead optimization, it is important to determine the basic characteristics of leads, and in order to make a compound a drug sample, at least five basic attributes need to be considered including potency, bioavailability, duration, safety, and pharmaceutical acceptability.LEARN MORE
In early drug development stage, placing a radioactive tag at a metabolically stable site on the investigational drug molecule represents an efficient strategy for investigating the disposition of a drug candidates. BOC Sciences offers stable isotope synthesis service that aim at compounds ranging from organic chemicals, such as polymers, to complex bioactive compounds, such as amino acids, peptides and some proteins. With extensive experience in radiochemistry, our clients in worldwide can be satisfied with highly rapid, accurate, and efficient drug discovery services in the fully customized ways.LEARN MORE
Bioconjugation is a set of techniques allowing site-specific creation of a covalent link between a biomolecule and an exogenous moiety that endow it with desirable properties. This novel hybrid having the combined properties of its individual components can serve, for instance, as a more stable and efficient therapeutic, an assembly for studying proteins in the biological context, a new protein-based material, a microarray, a biological material, a tool for immobilisation, and for elucidation of the structure of proteins.LEARN MORE
Majority of compounds contain certain amounts of impurities and will suffer from a certain extent degradation during production, storage, and transportation. Combined with a suite of advanced analytical techniques, scientists from BOC Sciences can offer the cost effect purification and reclamation services for our clients. More importantly, varying scale of isolation and purification ranged from a few milligrams to tens of grams is able to be conducted upon your needs. With knowing of the utmost importance of accuracy and efficiency to your drug development program, rapid and reliable impurity profiling will be provided by our experts who have extensive experience in solving various impurity issues.LEARN MORE
As one of the most key elements for any pharmaceutical development program, analytic method development, validation, and transfer plays an essential role in many aspects such as controlling the quality, ensuring the safety and improving the potency of products. BOC Sciences has extensive resources and lots of flexibility to develop analytical methods or perfecting the existing ones to tailor to your specific needs. With decades experience in designing and executing method development, validation protocols and technique or knowledge transfer, our experts are capable of providing assistance services throughout the entire development process.LEARN MORE
Based on the depth knowledge of properties of your drug candidates and inactive components, our scientists will guide you through decisions and provide advice to design the most appropriate formulations regarding the release characteristics or bioavailability. Our experts are specialized in designing and development of various dosage forms including tablets, capsules, creams, lotions, ointments, gels, non-sterile liquids and suspensions as well as sustained or extend formulations. To make ensuring that all your formulation needs can be met timely and your budgets are maintained, our highly skilled team will work closely with you and promptly provide you a comprehensive research report.LEARN MORE
With decades of experiences in the pharmaceutical industry, our experts have depth perception for the importance of adhering to the highest standards for quality, development of robust analytical procedures and efficiently testing and controlling the raw materials, intermediates and final products. At BOC Sciences, our quality control teams will work with you to establish a high standard criteria in all stages of drug development from laboratory process development to production through to regulatory data submission.LEARN MORE
BOC Sciences is a contract research organization (CRO) supporting pharmaceutical and biotechnology companies, research institutes and academic groups. We provide libraries and services for the early stage of drug discovery.
An equivalent of a big pharma discovery team from BOC Sciences will collaborate closely with you to make your project a success-from screening of drug candidates to delivering robust formulations. Our unparalleled platforms and excellent drug discovery expertise enable us to provide you the depth and breadth in science with comprehensive data and unique insight that can progress your drug discovery programs.
BOC Sciences offers dedicated services to support and accelerate fundamental research in academic laboratories, government institutions, non-governmental organizations and foundations.
BOC Sciences supports technology transfer organizations (TTO, SATT) in their valorization mission. We provide services that contribute to proof-of-concept programs and IP reinforcement needed for the development of innovations.
BOC Sciences offers a wide range of services for small molecule drug discovery. We help biotech and biopharma companies to address drug development challenges and provide the best quality research services.
BOC Sciences is a drug discovery partner for the pharmaceutical industries. We offer solutions from early discovery up to preclinical research phase.