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Chromatography Testing

Chromatography Testing

At BOC Sciences, we provide chromatography testing services for a wide range of research and industry needs. Our team uses advanced platforms such as HPLC, UHPLC, GC, IC, SEC/GPC, and 2D chromatography. We design methods, adjust workflows, and deliver accurate and reproducible results. Our services support drug development, biomolecule analysis, polymer characterization, and complex mixture testing. Every project receives tailored solutions to ensure efficiency and reliable data. With global experience and proven expertise, we help clients turn analytical results into clear insights and confident decisions.

Types of Chromatography Testing Services We Offer

HPLC Testing

High performance liquid chromatography (HPLC) is a cornerstone method in pharmaceutical and biomedical research. At BOC Sciences, our HPLC services support drug development, impurity profiling, and quality control. With a broad selection of columns and mobile phases, we can separate compounds with varying polarities and consistently produce high-quality, reliable data.

UHPLC Testing

Ultra-high performance liquid chromatography (UHPLC) extends HPLC capabilities by using smaller column particles, enabling faster analysis, improved resolution, and reduced solvent use. This method is ideal for complex mixture analysis and high-throughput screening in pharmaceutical R&D. Our UHPLC platforms deliver rapid, dependable results to help meet project timelines efficiently.

GC Testing

BOC Sciences provides advanced gas chromatography (GC) testing for volatile and semi-volatile compounds. Our GC systems, equipped with high-resolution detectors, are applied across drug analysis, environmental testing, and forensic studies. This technique separates and quantifies components that can be vaporized without decomposition, delivering highly reproducible results across diverse applications.

IC Testing

Ion chromatography (IC) allows precise separation and detection of ionic species, including cations, anions, and organic acids. BOC Sciences uses state-of-the-art IC instruments with conductivity detectors to accurately measure trace components in pharmaceuticals, food, and environmental samples.

SEC/GPC Testing

Size exclusion chromatography (SEC) and gel permeation chromatography (GPC) separate molecules based on size rather than chemical properties, making them essential for protein purification and polymer characterization. Our SEC/GPC services cover biomolecules, peptides, polysaccharides, and synthetic polymers, providing detailed insights into molecular weight distribution and sample purity.

2D Chromatography Testing

Two-dimensional chromatography combines two separation techniques to maximize resolution when single-dimension methods are insufficient. We apply 2D chromatography in metabolomics, proteomics, and complex drug formulations, delivering customized solutions tailored to your specific research or development needs.

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Chromatography Testing Sample Coverage

MTT Assay

Pharmaceuticals

We analyze active pharmaceutical ingredients (APIs), intermediates, and formulations. Our chromatography testing supports impurity detection, stability studies, and batch quality control to meet strict pharmaceutical standards.

CCK-8 Assay

Proteins and Peptides

Proteins, peptides, and other biomolecules require specialized separation methods. BOC Sciences applies SEC, HPLC, and ion chromatography to analyze molecular weight, purity, and aggregation, supporting biopharmaceutical development.

Caspase-3 Activity Assay

Lipids and Triglycerides

Chromatography is essential for lipidomics and triglyceride profiling. Using GC and LC-MS platforms, we deliver accurate analysis of fatty acids, triglycerides, and complex lipid mixtures in biomedical research.

LDH Assay

Plant Extracts

We test pigments, alkaloids, and bioactive compounds from plant sources such as spinach, kale, and flowers. Chromatography ensures reliable identification and quantification, supporting natural product research and nutraceutical studies.

BOC Sciences Chromatography Testing Clients

01

Academic Research Institutions

We provide a range of chromatography testing services for universities and research centers worldwide, supporting fundamental research, student training, and academic publications, helping researchers obtain reliable data.

02

Pharmaceutical and Biotech Companies

We offer comprehensive chromatography testing services for pharmaceutical and biotech companies, from early-stage compound screening to late-stage quality control, helping accelerate drug development and ensure compliance with industry standards.

03

Forensic and Drug Testing Agencies

We provide GC-MS and LC-MS analysis for forensic laboratories and drug testing agencies, helping accurately identify and quantify drugs, toxins, and controlled substances.

04

Food and Environmental Laboratories

We deliver chromatography testing for food and environmental laboratories, enabling precise detection of contaminants, residues, and pollutants in water, soil, and food products, supporting food safety and environmental protection.

05

Industrial and Polymer Research

We provide chromatography services such as SEC/GPC for industrial clients, supporting polymer and materials research by characterizing molecular weight distribution and composition to ensure R&D and production quality.

06

Daily Chemical Products Companies

We offer chromatography testing for daily chemical product manufacturers, detecting active ingredients, additives, and trace impurities, helping optimize formulation stability, enhance product safety, and strengthen quality assurance.

Chromatography Testing Workflow at BOC Sciences

At BOC Sciences, we follow a structured and transparent chromatography testing workflow to ensure accurate and reproducible results. Our streamlined process helps clients, from academic researchers to pharmaceutical companies, achieve reliable outcomes while saving time and resources.

Requirement Understanding

1Consultation

Every project begins with a detailed consultation to understand your research goals, sample type, and analytical requirements. Our experts work closely with you to recommend the most suitable chromatography testing method, whether GC, HPLC, LC-MS, ion chromatography, or size exclusion chromatography.

Experimental Design

2Sample Preparation

Proper sample preparation is critical for high-quality data. We provide standardized procedures such as filtration, extraction, and conditioning (e.g., using chromatography filter paper, silica gel, or resin columns) to ensure sample integrity and reproducibility.

Model System Construction

3Method Development

Our team tailor chromatography methods to your project's needs, including normal phase vs reverse phase chromatography selection, mobile and stationary phase optimization, and column choice. This step maximizes resolution and accuracy for complex mixtures.

Pharmacological Testing Execution

4Instrumental Analysis

Using advanced instruments such as gas chromatography analyzers, HPLC systems, LC-MS machines, and ion chromatography detectors, we perform precise separation and measurement of target compounds. Each run is conducted under strict quality controls.

Data Collection and Analysis

5Data Reporting

Results are delivered in clear, publication-ready formats, including chromatography graphs, size exclusion chromatography results, and detailed lab reports. We ensure traceable, high-quality data to support your research.

Report Delivery

6Ongoing Support

Our relationship does not end with data delivery. BOC Sciences provides continuous technical support, result interpretation, and guidance for follow-up testing, ensuring your projects progress smoothly.

BOC Sciences Service Advantages

Advanced Instruments

We utilize state-of-the-art gas chromatography, HPLC, LC-MS, and ion chromatography instruments to deliver highly precise and reproducible testing results.

Comprehensive Supplies

BOC Sciences provides full chromatography supplies, including silica gel, columns, cartridges, vials, and chromatography filter paper, ensuring seamless testing workflows.

Expert Team

Our chromatography testing services are supported by a team of experienced biochemists and pharmaceutical scientists dedicated to reliable data and tailored solutions.

Global Standards

All chromatography testing at BOC Sciences follows strict international quality standards, ensuring consistent, accurate, and trusted results for research and industry.

Chromatography Testing Case Studies and Success Stories

Client: An international academic research group and a materials science company

Challenge: The client required precise size exclusion chromatography (SEC) and gel permeation chromatography (GPC) analysis to measure molecular weight distribution of protein complexes and synthetic polymers for biomedical and industrial studies.

Solution: BOC Sciences utilized advanced high performance size exclusion chromatography (HPSEC) systems, carefully selecting the most suitable SEC resins and large-scale chromatography columns for each sample. We optimized the SEC procedure and detection parameters, generating high-resolution chromatography graphs, molecular weight distribution curves, and SEC results to provide comprehensive insights.

Outcome: The academic team successfully completed protein purification experiments and published high-impact research, while the industrial partner improved polymer manufacturing consistency and strengthened market competitiveness.

Client: A mid-size biopharmaceutical company in North America

Challenge: During new drug development, the client required impurity profiling, stability studies, and comparison of normal phase vs reverse phase chromatography to ensure optimal separation of drug formulations.

Solution: Our scientific team developed a customized HPLC testing protocol using advanced liquid chromatography systems and multiple column types. By optimizing mobile and stationary phase gradients, we achieved high-resolution separation of target compounds and impurities. We further enhanced quantification accuracy with LC-MS instruments.

Outcome: The client received reproducible, high-quality chromatograms and data, enabling smooth progression of drug development and accelerating project timelines.

Client: A well-known toxicology laboratory in Europe

Challenge: The client required highly sensitive GC-MS drug testing to detect trace amounts of controlled substances in complex urine and blood samples, while minimizing false positives.

Solution: BOC Sciences deployed multiple high-resolution gas chromatography instruments and GC-MS analyzers, integrating split injection techniques and high-sensitivity TCD/mass detectors. Our team optimized column selection and mobile phase conditions for different metabolites and delivered detailed chromatography graphs and quantitative reports, ensuring traceable results suitable for forensic applications.

Outcome: The client significantly improved detection sensitivity, reduced false positive rates, and delivered testing reports that were highly recognized by judicial authorities.

Master Chromatography Techniques – Download Whitepaper & Get Your Quote

Access essential chromatography resources, including guidance on column selection, mobile phase optimization, method setup, data interpretation, and detector usage tips.

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Applications of Chromatography Testing

Drug Testing

We provide sensitive, accurate GC and GC-MS drug testing for pharmaceutical studies.

Forensic Science

Chromatography supports forensic analysis, offering reliable results for toxicology and investigations.

Pharma Development

We enable chiral, phase, and LC-MS chromatography for precise drug characterization.

Biomedical Research

Advanced SEC, GPC, GC, and LC-MS techniques support protein, polymer, lipid analysis.

Frequently Asked Questions

Frequently Asked Questions

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