Metabolites of pharmaceutical compounds are pivotal to comprehending drug metabolism, potential drug interactions, and human drug metabolizing enzymes. Primary metabolites are synthesized by the cell because they are critical for biological growth like alcohols and vitamins. Secondary metabolites are the compounds produced by an organism. They are not essential for primary metabolic processes, although they can have important ecologic and other functions such as pesticides and drugs.
Metabolites synthesis is vital to advances in science and medicine today when investigators look for a deeper understanding of the chemical processes of cells or drug metabolism and apply those insights to new approaches to identifying diseases and discovering new treatments.
Application of Metabolites Synthesis
By understanding how small molecules can be transformed as part of biochemical processes, we can better correlate the impact of those treatment or drug on cell health. The synthesis and purification of considerable amounts of the metabolites provide reliable conclusions regarding the cardiotoxicity of drug metabolites and then pharmacological prevention or treatment of the disease side effects. Also, the metabolites, which are resistant to insect and microbial infections, help us adapt to the environment. Most of the known secondary metabolites are difficult and infeasible to obtain due to their unexplored chemical synthesis. In that case, we use an alternative biotechnology way for the production of such kind of metabolites like sugars, fatty acids, alkaloids, glycosides, flavonoids, volatile oils, tannins and resins etc. Despite the limited supply of metabolites, we would pursue different strategies to elicit the desirable product in feasible quantity and higher purity.
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