Metabolites Synthesis

Metabolites Synthesis

Metabolites synthesis is vital to advances in science and medicine today when investigators look for a deeper understanding of the chemical processes of cells or drug metabolism and apply those insights to new approaches to identifying diseases and discovering new treatments. BOC Sciences offers custom metabolites synthesis and manufacturing services for biotechnology, pharmaceutical, life science and chemical research.

What are Metabolites?

Metabolites are small molecules that are produced by living organisms as part of their metabolic processes. These molecules can be produced by a variety of different cellular pathways, including carbohydrate metabolism, lipid metabolism, and amino acid metabolism. Metabolites can be classified into two main groups: primary metabolites and secondary metabolites.

Primary metabolites are synthesized by the cell because they are critical for biological growth like alcohols and vitamins. Secondary metabolites are the compounds produced by an organism. They are not essential for primary metabolic processes, although they can have important ecologic and other functions such as pesticides and drugs.

Pharmacological Significance of Drug Metabolites

  • Drug metabolites can have a significant impact on the pharmacological activity, toxicity, and therapeutic efficacy of drugs.
  • Drug metabolites can also play a role in drug-drug interactions.
  • Drug metabolites can also be used as biomarkers for drug exposure and response.

Application of Metabolites Synthesis

By understanding how small molecules can be transformed as part of biochemical processes, we can better correlate the impact of those treatment or drug on cell health. The synthesis and purification of considerable amounts of the metabolites provide reliable conclusions regarding the cardiotoxicity of drug metabolites and then pharmacological prevention or treatment of the disease side effects. Also, the metabolites, which are resistant to insect and microbial infections, help us adapt to the environment. Most of the known secondary metabolites are difficult and infeasible to obtain due to their unexplored chemical synthesis. In that case, we use an alternative biotechnology way for the production of such kind of metabolites like sugars, fatty acids, alkaloids, glycosides, flavonoids, volatile oils, tannins and resins etc. Despite the limited supply of metabolites, we would pursue different strategies to elicit the desirable product in feasible quantity and higher purity.

Our Advantages

  • Equipped with a wide range of technologies, providing metabolites or bioactive compounds, phyto-pharmaceuticals occurring in plants cells.
  • With the help of professional experts from different areas, like Plant science, Pharmacognosy, Microbiology, Phyto-chemistry, Biochemistry, Molecular biology.
  • In quantities of several milligrams up to 100 grams.
  • Additional analyses, such as stability determination, impurity analysis, and residual solvents etc.
  • With diverse state-of-the-art technologies and approaches.
  • Quality assurance: HPLC chromatogram and Mass spec analysis.
  • Overnight shipping with suitable packs.


  1. Varela, C. L., Amaral, C., da Silva, E. T., Lopes, A., Correia-da-Silva, G., Carvalho, R. A., ... & Teixeira, N. (2014). Exemestane metabolites: synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line. European journal of medicinal chemistry, 87, 336-345.

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