BOC Sciences offers comprehensive UHPLC Testing services tailored to meet diverse client needs across research, development, and industrial applications. Our services cover over 1,000 sample types, including organic chemicals, natural products, small molecules, functional materials, and more. Leveraging a scientific team of over 50 experienced analysts, advanced instrumentation with high-pressure columns (< 2 μm particle size), and a global collaboration network spanning 20+ countries, we deliver reliable, reproducible, and actionable analytical results. From customized testing workflows to detailed reporting and data interpretation, our UHPLC services help clients optimize compound development, monitor quality, and accelerate innovation. With a focus on precision, efficiency, and client satisfaction, we provide trusted analytical support for complex sample analysis, achieving >95% client satisfaction across multiple industries.
Ultra-High Performance Liquid Chromatography (UHPLC) testing is a high-resolution analytical technique that builds on traditional liquid chromatography principles. By using high-pressure columns packed with very fine particles, often below 2 μm, and high-flow mobile phases, UHPLC achieves highly efficient separation of sample components. Compared with conventional HPLC, UHPLC can reduce peak widths by 50–70%, increase theoretical plate numbers by 3–5 times, and improve detection sensitivity for low-concentration compounds by up to 10-fold. For example, in natural product analysis, UHPLC-MS has successfully separated and quantified trace flavonoids in plant extracts at concentrations below 0.5 μg/mL, while UHPLC-DAD allows rapid profiling of complex organic mixtures. Coupled with multiple detectors such as MS, DAD, and ELSD, UHPLC provides both qualitative and quantitative insights. Its applications span organic chemicals, small molecule drugs, polymers, natural products, and functional materials, offering reliable, reproducible data that support research, compound development, and industrial quality control.
BOC Sciences' UHPLC Testing Services provide a comprehensive analytical platform to address diverse sample characterization needs. Leveraging UHPLC's high efficiency and flexibility, our services support precise molecular profiling, impurity analysis, and method optimization across research, development, and industrial applications. Our labs handle hundreds of samples weekly, ensuring fast turnaround while maintaining high reproducibility and traceable results.
Combines UHPLC's high-efficiency separation with mass spectrometry detection for precise qualitative and quantitative analysis, suitable for complex mixtures, trace components, and high-throughput screening.
High-resolution mass spectrometry (HRMS) coupled with UHPLC enables accurate molecular weight determination, structural elucidation, and trace component detection, providing sensitive analytical support for diverse chemical and material systems.
Size-exclusion chromatography (SEC) coupled with UHPLC separates molecules based on molecular size, ideal for polymers, proteins, and macromolecules, providing detailed molecular weight distribution information.
Capillary electrophoresis (CE) combined with UHPLC achieves highly efficient separation of charged or polar molecules, suitable for accurate analysis of small molecules and biomolecules.
Diode array detection (DAD) combined with UHPLC enables multi-wavelength analysis, suitable for reaction monitoring, impurity profiling, and chromophoric compound analysis.
Evaporative light scattering detection (ELSD) coupled with UHPLC enables detection of non-UV absorbing compounds, such as lipids, sugars, and other challenging molecules, expanding UHPLC's analytical capabilities.
If you don't see the UHPLC testing service that fits your sample or project, contact us directly. Our expert team will create a customized solution and deliver a clear, tailored quotation.
Covers a wide range of synthetic chemicals, raw materials, and intermediates, providing accurate qualitative and quantitative analysis to support research, development, and quality control.
Supports comprehensive analysis of plant extracts, complex natural product mixtures, and their derivatives, enabling precise component identification and reliable data for R&D projects.
Suitable for drug candidates, functional small molecules, and laboratory chemicals, offering detailed profiling, impurity detection, and quantitative assessment to ensure consistent quality.
Encompasses polymers, nanomaterials, and other functional chemical materials, delivering high-resolution analysis for structural characterization, performance evaluation, and product development optimization.
Includes active ingredients, formulation components, and potential impurities, providing accurate quantification and purity assessment to support safe and effective cosmetic product development.
Supports analysis of food and beverage additives, nutritional components, and trace impurities, ensuring precise identification, quantification, and quality verification for manufacturing and R&D.
To ensure accurate and efficient UHPLC testing, please provide your sample name, type, quantity, and concentration, along with the required analysis type, project background, special requirements, and preferred report format or delivery method. Upon submission, our expert team will review the information, confirm sample suitability, discuss any additional details, and provide a personalized quote.
We provide UHPLC-MS, UHPLC-HRMS, and UHPLC-DAD analytical services to support molecular structure elucidation, impurity screening, and component quantification. Through high-resolution separation and sensitive detection, our services help R&D teams optimize compound design, ensure the quality of research samples, and accelerate the evaluation of new drug candidates.
For raw material suppliers, we offer comprehensive component analysis, impurity detection, and content determination. Using UHPLC-ELSD and UHPLC-DAD techniques, we ensure raw material consistency and batch control, enhancing supply chain quality management and building customer trust.
Nutraceutical companies can utilize our UHPLC testing services for active ingredient quantification, component combination analysis, and impurity profiling. Covering both natural products and small molecule compounds, our services help verify raw material efficacy, optimize formulations, and ensure accurate product labeling.
For the food and beverage industry, we provide UHPLC-DAD and UHPLC-ELSD analyses for additive detection, flavor component analysis, and trace impurity monitoring. Our precise data support product development, formulation improvement, and quality control, enhancing production efficiency and safety.
Cosmetic R&D teams can use our UHPLC-SEC, UHPLC-DAD, and UHPLC-MS services to analyze active ingredients, formulation combinations, and potential impurities. Our services help optimize product performance, assess stability, and ensure final formulation quality.
We offer flexible, customized UHPLC analysis solutions for academic and research institutions, including qualitative and quantitative analysis of small molecules, natural products, and functional materials. Our services support data collection, method development, and complex sample analysis, meeting the diverse needs of innovative research projects.
Before starting the service, we conduct in-depth communication with clients to clarify sample types, analysis objectives, and specific requirements. By understanding the client's project background, we can design an optimal testing strategy to ensure accurate and efficient subsequent analysis.
The sample reception process is strictly managed, including sample registration, labeling, storage, and recommendations for pre-treatment procedures. For samples with different properties, we provide customized handling to ensure sample integrity and traceability throughout the analysis process.
We select the appropriate UHPLC-based detection method according to client requirements, such as UHPLC-MS or UHPLC-DAD. Each step follows standardized procedures to ensure high-resolution, reproducible, and sensitive results that meet both research and industrial application needs.
Raw data are processed using professional software and analyzed by our expert team, including peak identification, quantitative calculation, and component confirmation. Our team applies professional judgment to ensure scientifically reliable results and provides support for further data interpretation.
A detailed analytical report is generated based on the results, including experimental data tables, chromatograms, peak analysis, and qualitative and quantitative outcomes. The report is clear and comprehensive, suitable for research, raw material verification, or quality management purposes.
After report delivery, we proactively communicate with clients to address questions and collect feedback. By continuously improving analytical methods and service workflows, we ensure client satisfaction and foster long-term collaboration.
Coupled with UHPLC (UHPLC-MS/HRMS), it enables precise qualitative and quantitative analysis after high-resolution separation, identifying trace components and impurities in complex samples, and providing critical data for molecular structure elucidation.
Used in combination with UHPLC-separated target components to perform structural and conformational analysis, supporting precise structure confirmation of natural products, functional molecules, and small molecules.
Coupled with UHPLC-DAD, it monitors separated components at multiple wavelengths for qualitative and quantitative analysis, supporting reaction monitoring and impurity detection.
After UHPLC separation, it detects specific active or labeled components via fluorescence, suitable for trace component analysis and enhancing detection sensitivity.
Coupled with UHPLC, it enables high-efficiency separation of charged or highly polar molecules, suitable for small molecules and biomolecular component analysis, improving separation performance and resolution.
Used after UHPLC separation to detect non-UV absorbing compounds such as sugars, lipids, and other challenging molecules, expanding UHPLC application range and providing full component coverage.
Equipped with multiple high-precision UHPLC and hyphenated instruments, ensuring broad analytical coverage, high sensitivity, and capability to handle complex samples.
Our experienced analytical team is proficient in a wide range of testing methods, capable of designing optimal analysis plans tailored to different client samples.
Long-term collaborations with domestic and international research institutions and enterprises ensure technical exchange, resource sharing, and reliable service delivery.
Flexible solutions tailored to client project requirements, including sample pre-treatment, method selection, and result interpretation, supporting diverse R&D and industrial needs.
Efficient communication and technical support allow timely resolution of issues related to sample analysis, data interpretation, and method optimization.
A rigorous data management system ensures the confidentiality, integrity, and traceability of client samples and analytical results.
Access essential chromatography resources, including guidance on column selection, mobile phase optimization, method setup, data interpretation, and detector usage tips.
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Client: A leading botanical extract manufacturer in North America
Challenge: The client needed precise identification and quantification of multiple active compounds in complex plant extracts to ensure batch consistency and optimize extraction processes.
Solution: BOC Sciences applied UHPLC coupled with high-resolution mass spectrometry (UHPLC-HRMS) to separate and identify target compounds. Customized sample preparation protocols and optimized chromatographic conditions were implemented for each extract. Detailed chromatograms, peak analysis, and quantitative reports were provided to the client.
Outcome: The client achieved reliable component profiling, improved batch-to-batch consistency, and accelerated R&D for new botanical formulations.
Client: A pharmaceutical R&D company in Europe
Challenge: The client required accurate detection of impurities and quantification of small molecule intermediates in synthetic reactions to support quality control without delaying production timelines.
Solution: BOC Sciences employed UHPLC-DAD for high-resolution separation and multi-wavelength detection of reaction products and impurities. Our team optimized mobile phase gradients, flow rates, and detection wavelengths to ensure precise quantification. Comprehensive reports including peak purity, chromatograms, and quantitative analysis were delivered.
Outcome: The client was able to monitor reaction processes more effectively, reduce impurity levels, and maintain consistent product quality, enabling faster scale-up and process optimization.
Client: A specialty chemical manufacturer in Asia
Challenge: The client needed detection and quantification of non-UV-absorbing functional polymers and lipid-based materials in complex mixtures for R&D and quality assurance.
Solution: BOC Sciences applied UHPLC coupled with evaporative light scattering detection (ELSD). Our team developed tailored chromatographic conditions and sample preparation methods for each polymer and lipid component. Analytical reports included detailed chromatograms, peak analysis, and quantitative results.
Outcome: The client achieved accurate profiling of challenging functional materials, improved formulation consistency, and gained actionable insights for product development and quality control.
UHPLC utilizes smaller particle columns (<2 μm) and higher pressure, resulting in faster separation, narrower peaks, greater resolution, and higher detection sensitivity than traditional HPLC.
Yes. We tailor testing workflows, detection methods, and reporting formats based on sample type, analysis goals, and client requirements, ensuring precise, actionable results for R&D, QC, or product development.
Clients can submit samples via our Sample Submission Form, providing sample details, quantity, type, desired analysis, project background, and any special requirements. Our team will carefully review the information and confirm suitability before proceeding.
After sample confirmation, turnaround time depends on sample type and analysis scope. Clients typically receive preliminary feedback within days, with full analytical reports delivered efficiently according to project requirements.
We combine advanced UHPLC instrumentation with experienced analysts, standardized protocols, and rigorous data validation to guarantee reproducible, traceable, and accurate analytical results for diverse samples.
BOC Sciences provided highly reliable UHPLC testing support for our complex small-molecule project. Their team demonstrated strong expertise in method development and impurity profiling, delivering accurate results within tight timelines. The structured reports and clear data interpretation helped our R&D team accelerate decision-making and reduce analytical turnaround by nearly 30%. We consider BOC Sciences a trusted partner for analytical excellence.
— Dr. S., Senior Scientist, Global Pharmaceutical Company
The UHPLC testing service from BOC Sciences consistently delivers high-precision data with excellent reproducibility. Their rigorous approach to system suitability and impurity profiling gave us full confidence in the analytical outcomes. This level of quality has been instrumental in supporting our internal QA reviews.
— Dr. L., Director of Quality Control, Mid-sized Biotech Company
We were impressed by BOC Sciences' ability to customize UHPLC methods to our project requirements. The team responded quickly to evolving priorities, ensuring rapid turnaround without compromising accuracy. Their flexible approach helped us stay on track with critical project deadlines.
— Mr. K., Project Manager, European CDMO
BOC Sciences not only provided robust UHPLC testing results but also delivered comprehensive documentation aligned with international reporting standards. Their attention to detail in traceability, raw data integrity, and reporting format made tech transfer to our manufacturing partners seamless.
— Ms. R., Associate Director, US Pharmaceutical Company
