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Hyphenated Spectroscopic Techniques

Hyphenated Spectroscopic Techniques

BOC Sciences offers a comprehensive range of hyphenated spectroscopic testing services, including LC-MS, LC-NMR, LC-HRMS, GC-IR, GC-FTIR, GC-MS, GCxGC, and other related services. By combining high-efficiency separation techniques with advanced spectroscopic detection, we provide highly sensitive, accurate, and detailed structural and compositional analysis across pharmaceutical, chemical, materials, food, and environmental samples. Our end-to-end services, from method development and sample testing to data interpretation and professional reporting, deliver reliable, reproducible results, supporting research, product development, and quality control with precision and efficiency.

Hyphenated Spectroscopic Testing Services Catalog

LC-MS Testing

BOC Sciences provides LC-MS testing that combines high-efficiency liquid chromatography separation with mass spectrometric detection, enabling highly sensitive qualitative analysis of complex samples. It is widely applied in chemical, food, and environmental component identification.

LC-HRMS Testing

High-resolution mass analysis is available through BOC Sciences' LC-HRMS service, offering precise mass measurements and trace component detection. It supports molecular formula confirmation and advanced qualitative analysis for complex sample matrices.

LC-NMR Testing

Through LC-NMR testing at BOC Sciences, molecular structures can be directly elucidated after separation. This service is ideal for purity analysis and structural characterization of complex compounds, delivering reliable qualitative information for research and quality control.

GC-IR Testing

GC-IR testing at BOC Sciences combines gas chromatographic separation with infrared functional group detection, providing accurate structural information for volatile and semi-volatile compounds, and is widely used in chemical and materials research.

GC-FTIR Testing

With GC-FTIR testing from BOC Sciences, high-resolution Fourier-transform infrared spectroscopy is integrated with chromatographic separation. This approach enables detailed qualitative structural analysis of complex mixtures, suitable for research, quality control, and component identification.

GC-MS Testing

BOC Sciences' GC-MS service delivers efficient separation combined with mass spectrometric detection, offering qualitative and semi-quantitative data. It is extensively applied for environmental, food, and chemical sample analysis.

GCxGC Testing

Using two-dimensional gas chromatography, BOC Sciences' GCxGC service significantly enhances separation of complex samples. When coupled with mass spectrometry or spectroscopy, it enables precise component separation and structural elucidation in high-complexity matrices.

Looking for detailed structural and compositional analysis?

Unlock the full potential of your experiments with our advanced hyphenated spectroscopic testing services. Accurate analysis, reliable results, faster insights.

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Tailored Spectroscopy Solutions for Diverse Needs

MTT Assay

Solution for Pharmaceutical and Biotech Companies

Spectroscopy is widely applied for molecular structure confirmation, impurity identification, and stability or quality assessments. Pharmaceutical and biotech firms often face challenges such as limited in-house instrumentation, complex sample matrices, and high-precision requirements. Our hyphenated spectroscopic testing services provide reliable structural and quantitative insights, supporting research and development, process optimization, and consistent quality control across diverse projects.

CCK-8 Assay

Solution for Chemical Companies

Chemical manufacturers require accurate compositional analysis, reaction monitoring, and product quality verification. Complex chemical matrices and demanding analytical specifications often exceed standard laboratory capabilities. Our hyphenated spectroscopic services offer precise, reproducible data for structural characterization, impurity profiling, and process optimization, ensuring efficient development and reliable product performance.

Caspase-3 Activity Assay

Solution for Food and Beverage Industry

Food and beverage companies face strict requirements for composition analysis, additive detection, and safety or quality monitoring. Samples are often complex and varied, requiring advanced analytical approaches. Our spectroscopy testing services provide comprehensive qualitative and quantitative data, enabling accurate ingredient verification, contamination assessment, and consistent product quality control.

LDH Assay

Solution for Materials Companies

Material developers need detailed structural and compositional information to optimize formulations and validate performance. Challenges include heterogeneous sample matrices and multi-component systems. BOC Sciences' hyphenated spectroscopic services deliver high-resolution analysis, structural elucidation, and component quantification, supporting material innovation, process refinement, and reliable quality assurance.

Enhance Your R&D with Custom Spectroscopic Services

BOC Sciences' hyphenated spectroscopic techniques offer comprehensive, precise data for structural and compositional analysis. Partner with us to design a testing workflow that fits your project requirements.

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Hyphenated Spectroscopic Techniques Service Process

Requirement Understanding

1Consultation and Requirement Confirmation

Clients provide sample information and testing goals. Our experts discuss objectives, sample type, and recommend the most suitable hyphenated spectroscopic approach.

Experimental Design

2Sample Submission and Reception

Clients securely send samples to our lab. Upon arrival, samples are registered and inspected to ensure proper condition for accurate analysis.

Model System Construction

3Test Plan Design

Our team designs a customized analytical plan, selecting appropriate instrument combinations and optimizing parameters for reliable, efficient hyphenated spectroscopic testing.

Pharmacological Testing Execution

4Experiment Execution and Data Collection

Tests are conducted under controlled conditions using advanced hyphenated instruments, capturing high-quality spectra to ensure precise, reproducible results.

Data Collection and Analysis

5Data Processing and Analysis

Raw data are processed and analyzed, producing clear spectra, peak interpretations, and relevant qualitative or quantitative information for comprehensive understanding.

Report Delivery

6Report Preparation and Delivery

A professional report is generated, including methods, data, charts, and conclusions. Clients receive electronic access and optional technical support for interpretation.

Comprehensive Hyphenated Spectroscopic Report Overview

Basic Information and Overview

  • Client details, sample ID, and batch number
  • Report number, issue date, and version
  • Testing purpose, scope, and sample summary
  • Brief description of hyphenated technique used

Experimental Methods and Test Results

  • Instrument model, configuration, and analysis conditions
  • Sample preparation and injection procedures described
  • Raw data, spectra, and peak analysis included
  • Qualitative and quantitative results presented clearly

Results Discussion and Appendices

  • Key findings and component identification explained
  • Critical peaks or signals interpreted and discussed
  • Instrument calibration, standards, and data appendix
  • Analyst, reviewer signatures, and company stamp

Our Distinctive Advantages in Hyphenated Spectroscopy

01

Integrated Platform Capability

BOC Sciences offers advanced hyphenated spectroscopic platforms, seamlessly combining LC-MS/MS, GC-MS, and LC-NMR for comprehensive structural elucidation and multidimensional molecular insights.

02

Expert Team Proficiency

Our specialists average over eight years' experience in hyphenated techniques, designing optimal analytical strategies to ensure reliable, high-quality data interpretation for complex samples.

03

Extensive Project Experience

BOC Sciences has successfully addressed diverse projects involving natural products, functional materials, and small molecules, delivering innovative analytical solutions for challenging molecular structures.

04

Strong Global Partnerships

Through collaborations with leading instrument manufacturers and research institutions, we provide cutting-edge techniques and tailored solutions aligned with international scientific trends.

Applications for Hyphenated Spectroscopy Techniques

Pharmaceuticals & Life Sciences

Food & Nutrition Testing

  • Food Safety Testing
  • Nutrient Composition Analysis
  • Food Adulteration Detection
  • Functional Ingredient Research

Chemicals & Environmental Monitoring

  • Environmental Pollutant Analysis
  • Petrochemical Product Analysis
  • Polymer Material Characterization
  • Fine Chemicals Development

Hyphenated Techniques Testing Case Studies and Success Stories

Client: A specialty chemical company focusing on bioactive compounds

Challenge: The client needed structural elucidation and purity assessment of novel natural products, where minor impurities and isomeric forms could not be distinguished by traditional methods.

Solution: BOC Sciences implemented high-performance liquid chromatography coupled with nuclear magnetic resonance (HPLC-NMR). The approach enabled real-time structural analysis during chromatographic separation, providing detailed insights into molecular frameworks and stereochemistry. Our workflow included optimized solvent systems, flow rates, and NMR acquisition parameters, alongside post-processing for high-resolution spectra.

Outcome: The client obtained precise structural profiles of complex natural extracts, allowing confident selection of target compounds and efficient decision-making for downstream synthesis and product development.

Client: A leading environmental testing laboratory in North America

Challenge: The client needed accurate identification and quantification of trace organic pollutants in water and soil matrices, where complex sample backgrounds often interfered with conventional analysis.

Solution: BOC Sciences implemented liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), optimizing gradient elution programs and MS fragmentation parameters. Our team employed hyphenated techniques combining high-resolution LC separation with targeted MS/MS detection, enabling simultaneous multi-compound profiling with minimal matrix interference. Comprehensive data processing workflows generated precise spectra and quantitative tables.

Outcome: The client achieved highly reliable detection of low-level pollutants across diverse environmental samples, with enhanced throughput and reduced analysis variability, supporting advanced environmental monitoring initiatives.

Client: A global petrochemical manufacturer

Challenge: The client required detailed compositional analysis of complex hydrocarbon mixtures to optimize product quality and R&D development. Conventional single-technique analysis lacked the resolution and specificity to differentiate overlapping compounds.

Solution: BOC Sciences applied gas chromatography coupled with infrared spectroscopy (GC-IR), leveraging hyphenated detection to separate complex fractions and obtain molecular fingerprint information simultaneously. We customized column selection, temperature programming, and IR detector settings to match diverse hydrocarbon classes. Detailed spectral libraries and chromatograms were delivered for precise compound identification.

Outcome: The client gained rapid and accurate characterization of multi-component hydrocarbon blends, improving process control decisions and facilitating targeted formulation improvements.

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