Polymers have been widely used in field of biomedicine due to their biodegradability, relative biocompatibility, mechanical strength, conductivity and stimuli responsiveness properties. The solubility, immune-compatibility, pharmacokinetics or stability of many proteins can be improved by conjugation to polymers. A large number of polymers, which can be naturally occurring (such as chitosan, dextrans) or synthetic (such as poly(ethylene) glycol, N-(2-hydroxypropyl) methacrylamide copolymer), have the ability to conjugate with antibodies. Antibody conjugation to polymers directed against tumor-associated antigens is a new research area for scientist. The drug delivery system, which composed by polymers and their conjugates with antibodies, fragments of antibodies or oligopeptides, is suitable as carriers mainly for anticancer or anti-inflammatory agents. Antibody-polymer conjugates (APCs) are highly sensitive and specific, and their greatest advantage is high drug efficacy as well as extremely low toxicity. APCs have some functional similarities to antibody drug conjugates (ADC), and are mainly used in ELISA assays, Western blot and immunohistochemistry.
BOC Sciences has extensive expertise in research and development of antibody conjugate and offers you the best quality antibody-polymer conjugations in the industry. We have stringent quality assurance and quality control standards to meticulously monitor each antibody-polymer conjugate. The following is our products range:
For your antibody conjugation requirements, our experts of bioconjugation chemistries can provide you one-stop solution from the project design to the final delivery. Please contact us for more information and see how we can meet your bioconjugation needs.