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GC-MS Testing

GC-MS Testing

BOC Sciences is committed to offering comprehensive GC-MS testing services designed to meet the diverse needs of both research and industrial applications. Leveraging state-of-the-art instrumentation and the expertise of our experienced analytical scientists, we deliver precise identification and quantification of complex chemical compounds. From environmental samples and food and beverage matrices to industrial chemicals and natural products, we provide actionable analytical results that support clients in product development, quality control, and scientific research. Backed by extensive project experience and strong client recognition, our GC-MS services are trusted for their reliability, flexibility, and professional excellence.

What is GC-MS Testing?

GC-MS, or Gas Chromatography-Mass Spectrometry, is an analytical technique that combines the separation capabilities of gas chromatography with the identification power of mass spectrometry. Gas chromatography separates individual components in a complex mixture based on volatility and interaction with the column material. The separated compounds then enter the mass spectrometer, where they are ionized, fragmented, and detected according to their mass-to-charge ratios. This dual approach enables highly sensitive, accurate, and detailed chemical analysis. GC-MS is widely used across research, environmental, and industrial applications for detecting trace compounds, verifying chemical composition, and providing in-depth molecular information.

Advanced GC-MS Testing Services for Research and Quality Control

Quadrupole GC-MS

Provides routine qualitative and quantitative analysis of organic compounds. Ideal for laboratories requiring reliable, high-throughput analysis of standard samples. At our facilities, experiments are optimized based on sample characteristics to deliver accurate and reproducible results, supporting research, quality control, and method development.

GC-MS/MS

Offers high-sensitivity analysis, particularly suited for complex matrices and trace-level detection. This technique enables precise identification and quantification of target analytes in challenging samples, providing clients with robust analytical data to support advanced research and development projects.

GC-TOF-MS

Delivers high-resolution and non-targeted analysis, ideal for comprehensive profiling of complex mixtures. This service is particularly beneficial for natural products, metabolomics studies, and environmental screening, enabling detailed characterization of molecular compositions.

Headspace-GC-MS

Specialized for direct analysis of volatile compounds in gaseous samples. Suitable for VOC profiling in environmental, food, and fragrance applications, this method ensures sensitive and accurate detection of volatile analytes without extensive sample preparation.

Solid-Phase Microextraction (SPME)-GC-MS

Designed for trace-level extraction and analysis of volatile and semi-volatile compounds. By combining SPME with GC-MS, this service allows for non-invasive sampling, minimal matrix interference, and enhanced detection sensitivity, supporting R&D, quality control, and environmental monitoring applications.

Looking for Other GC-MS Services?

Contact us with your sample details and analytical goals, and we will recommend the GC-MS techniques best suited to your project needs.

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Sample Types Supported by Our GC-MS Testing

MTT Assay

Sample Scope

  • Chemical and Pharmaceutical Intermediates: Small organic molecules and impurities.
  • Biological Samples: Metabolites, drugs, and derivatives from blood or urine.
  • Material Extracts: Low molecular weight compounds from polymers and coatings.
  • Environmental Samples: Water, soil, and air organic pollutants analysis.
  • Food and Beverages: Pesticide residues, flavor compounds, and additives.
CCK-8 Assay

Basic Requirements for Samples

  • Sample Quantity: Typically 0.5–5 mL liquid or 0.1–1 g solid.
  • Sample Form: Homogeneous, free from visible impurities or sediment.
  • Containers: Sealed, chemically resistant glass or high-quality plastic bottles.
  • Solvent Compatibility: Use volatile solvents compatible with GC-MS analysis.
  • Information Provided: Sample source, treatment method, and target analytes.

GC-MS Analysis – Sample Submission Portal

Submit your samples for GC-MS testing with required information and sample details.

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Versatile GC-MS Instrument Platform

Our GC-MS service platform offers a comprehensive suite of high-performance instruments capable of analyzing a wide variety of sample types. Designed to support routine analysis, trace-level detection, and high-resolution compound characterization, our services meet the needs of environmental monitoring, food safety, pharmaceutical research, and advanced R&D projects. Key GC-MS instrument capabilities:

Instrument TypeKey FeaturesTypical Applications
Quadrupole GC-MSMost common, cost-effective, suitable for routine qualitative and quantitative analysisEnvironmental monitoring, food residue analysis, drug screening
Ion-Trap GC-MSHigh sensitivity, supports multi-stage fragmentationLow-concentration trace analysis, forensic toxicology
TOF GC-MSHigh resolution, wide mass rangeComprehensive profiling of complex mixtures, metabolomics
Triple-Quad GC-MS/MSSRM/SIM modes for targeted monitoringTarget compound quantification, pesticide residue, pharmacokinetics
HRAM GC-MS/MSCombines high resolution with quantitative capabilityUnknown compound identification, persistent organic pollutants (POPs) in the environment

GC-MS Testing Service Workflow

Requirement Understanding

1Consultation and Requirement Confirmation

Clients submit their sample details and analysis goals. Our experts clarify objectives, sample type, and detection needs for accurate GC-MS planning.

Experimental Design

2Sample Reception and Preparation

Samples are securely received, labeled, and recorded. Necessary preparation, such as extraction, dilution, or concentration, ensures compatibility with GC-MS analysis.

Model System Construction

3Method Design and Analysis

Our scientists design or optimize GC-MS methods based on sample characteristics, then perform analysis using advanced instrumentation for precise, reproducible results.

Pharmacological Testing Execution

4Data Processing and Quality Control

Raw data undergo processing, including peak identification, qualitative and quantitative analysis, with strict quality control ensuring reliable, scientifically sound results.

Data Collection and Analysis

5Report Generation and Delivery

A detailed GC-MS report is generated, including methods, data, and charts. Clients receive a secure electronic copy for review and documentation.

Report Delivery

6Client Support and Follow-Up

Post-delivery, clients can consult our experts for data interpretation, method optimization, or additional testing guidance, ensuring maximum utilization of results.

Accelerate Your R&D with GC-MS Testing Services

Leverage BOC Sciences' GC-MS testing solutions to obtain reliable compound separation, detailed mass spectra, and accurate molecular characterization for diverse sample types, enabling fast, efficient decision-making and streamlined progress in research and development projects.

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Analytical Test Report by BOC Sciences

Sample Information and Preparation

  • Sample type, batch number, and source
  • Sample physical state and storage conditions
  • Pre-treatment method used before analysis
  • Sample receiving and testing dates recorded

Instrument and Method Details

  • GC-MS instrument model and manufacturer specified
  • Chromatographic column type and dimensions listed
  • Injection mode, carrier gas, and flow rate
  • Detection mode and quantification method described

Test Results and Analysis

  • Detected compounds with retention times identified
  • Mass spectra and library match information provided
  • Quantitative concentrations, LOD, and LOQ included
  • Chromatograms and spectra visualized for review

BOC Sciences GC-MS Testing: Distinct Advantages

High Sensitivity Analysis

BOC Sciences utilizes advanced GC-MS instruments capable of detecting trace components down to low ppb levels, ensuring accurate identification in complex chemical samples.

Extensive Sample Handling Expertise

Our team has processed thousands of chemical compounds, optimizing sample preparation methods to ensure high reliability and reproducibility across diverse chemical matrices.

Customized Data Interpretation

We provide professional mass spectrometry data analysis, including structure identification, spectral comparison, and semi-quantitative analysis, tailored to support research and development decisions.

High Throughput and Flexible Service

BOC Sciences accommodates single samples to hundreds per batch, offering flexible workflows compatible with liquids, solids, and complex mixtures for efficient project management.

Broad Applications of GC-MS Services

BOC Sciences provides GC-MS services that cater to multiple application fields, spanning but not limited to the ones listed below.

Pharmaceutical & Life Sciences

Food & Environmental Safety

  • Food Component Analysis
  • Pesticide Residue Detection
  • Environmental Pollutant Monitoring
  • Flavor & Fragrance Analysis

Chemical & Materials Analysis

  • Fine Chemicals Characterization
  • Petroleum & Fuel Testing
  • Polymer Volatile Analysis
  • Material Degradation Products

GC-MS Testing Case Studies and Success Stories

Client: A mid-sized pharmaceutical R&D laboratory

Challenge: The client required precise identification and quantification of active pharmaceutical ingredients (APIs) and trace degradation products in complex formulations, where overlapping peaks could hinder accurate analysis.

Solution: BOC Sciences deployed high-resolution GC-MS systems with optimized derivatization protocols and selective ion monitoring (SIM). Our experts fine-tuned column selection, temperature gradients, and injection techniques to achieve clear separation of closely related compounds. Detailed chromatograms and mass spectra were provided, enabling precise qualitative and quantitative assessments.

Outcome: The client achieved high-confidence detection of low-abundance impurities and degradation products, improving formulation quality analysis and accelerating R&D iterations. Analytical reliability and reproducibility were significantly enhanced.

Client: A premium skincare manufacturer

Challenge: The client needed to identify and quantify volatile and semi-volatile fragrance and active ingredients in complex cosmetic formulations, including lotions and creams, where matrix effects could interfere with detection.

Solution: BOC Sciences implemented GC-MS combined with headspace and SPME sampling techniques to efficiently extract volatiles from complex matrices. Column types and temperature programs were optimized for a wide range of esters, alcohols, and terpenes. High-sensitivity mass detection ensured trace components were accurately captured.

Outcome: The client received detailed compositional reports of fragrance and active ingredients, supporting product development, batch consistency checks, and quality optimization. Testing throughput and accuracy were markedly improved.

Client: A global generic drug manufacturer

Challenge: The client required monitoring of chemical stability and identification of trace degradation compounds in tablets and liquids under different storage conditions, where precise separation and detection were critical.

Solution: BOC Sciences applied advanced GC-MS with tailored sample preparation, including derivatization and solvent extraction for challenging matrices. Our team optimized split ratios, injection modes, and mass spectrometer settings to capture both major and trace compounds. Comprehensive chromatographic and spectral analysis enabled detailed profiling of all relevant components.

Outcome: The client achieved consistent, reliable detection of degradation products, facilitating formulation optimization and ensuring high-quality standards. Analytical efficiency and sensitivity were significantly enhanced across multiple product lines.

Frequently Asked Questions

Client Reviews: GC-MS Testing Services

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