BOC Sciences offers comprehensive HPLC testing services covering a wide range of sample types, including small molecules, peptides and oligonucleotides, natural product extracts, polymers, food additives, and complex mixtures. Our services include quantitative analysis, qualitative analysis, impurity detection, purity assessment, method development, and stability studies, supporting the diverse needs of research institutions, pharmaceutical and biotech companies, chemical manufacturers, and the food and nutraceutical industries. Leveraging advanced HPLC and hyphenated techniques such as HPLC-MS, HPLC-NMR, and HPLC-ICP-MS, combined with an expert analytical team and strict quality management systems, BOC Sciences delivers highly sensitive, accurate, and actionable results to optimize R&D and quality control processes.
High-Performance Liquid Chromatography (HPLC) is based on the differential interactions of compounds with two phases: a stationary phase, packed inside the column, and a mobile phase, which flows through it. Each compound in a mixture has unique chemical properties, such as polarity, solubility, or size, that influence how strongly it binds to the stationary phase or travels with the mobile phase. As a result, individual components move at different speeds and are separated with high resolution.
The separated compounds are then detected by instruments such as UV, fluorescence, or mass spectrometry detectors. This produces a chromatogram that reveals both the identity and quantity of the components, enabling precise analysis for research, development, and quality evaluation across multiple industries.
HPLC-MS (Liquid Chromatography-Mass Spectrometry) combines the separation power of HPLC with the detection and identification capabilities of mass spectrometry. This technique offers high sensitivity and selectivity, making it ideal for analyzing complex samples such as pharmaceuticals, natural products, and biochemical compounds.
HPLC-NMR (Liquid Chromatography-Nuclear Magnetic Resonance) integrates HPLC separation with NMR structural elucidation, providing detailed insight into the molecular structures of components in complex mixtures. This technology is particularly suitable for natural products, biofluids, and other samples.
HPLC-ICP-MS (Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry) combines HPLC's separation capability with the high sensitivity of ICP-MS, allowing trace element analysis, including heavy metals detection. It is widely applied in environmental, pharmaceutical, and industrial testing.
HPLC-GC (Liquid Chromatography-Gas Chromatography) merges HPLC separation with the volatile compound analysis capability of GC. This hybrid technique is ideal for profiling volatile components in complex matrices, enabling comprehensive characterization of chemical mixtures.
HPLC-CE (Liquid Chromatography-Capillary Electrophoresis) combines the strengths of HPLC and capillary electrophoresis to separate complex mixtures with high resolution. This technique is effective for analyzing peptides, proteins, and other charged molecules where standard HPLC may be insufficient.
HPLC-UV/Vis (Liquid Chromatography-Ultraviolet/Visible Detection) integrates conventional HPLC separation with ultraviolet or visible light detection, enhancing analytical information. It is widely used for routine compound quantification and purity assessment in research and industrial applications.
HPLC-FTIR (Liquid Chromatography-Fourier Transform Infrared Spectroscopy) combines HPLC separation with FTIR structural analysis, providing detailed information about molecular bonds and functional groups. This approach is suitable for complex organic mixtures and natural product characterization.
HPLC-FTS (Liquid Chromatography-Thermal Lens Spectroscopy) integrates HPLC separation with thermal lens spectroscopy, enabling sensitive detection of specific analytes, such as pigments in marine phytoplankton or other specialized biochemical compounds.
Multidimensional HPLC employs multiple separation dimensions to improve resolution and analytical capacity for highly complex samples. It is particularly effective for mixtures with overlapping peaks or closely related compounds, enhancing the depth and reliability of analysis.
Due to space limitations, we cannot display all of our HPLC testing services. Please contact us to share your specific requirements, and our experts will provide a tailored solution and personalized quote.
We analyze a wide range of small molecule compounds, including intermediates, APIs, and specialty chemicals, providing accurate separation and quantification for research and production support.
Our services cover peptide and oligonucleotide analysis, offering high-resolution separation and sensitive detection to support synthesis verification, characterization, and experimental studies.
We handle complex botanical and natural product extracts, providing detailed profiling, component identification, and quantification to support R&D, quality assurance, and natural compound studies.
From synthetic polymers to specialty industrial chemicals, our HPLC testing ensures reliable characterization of composition, impurities, and stability, aiding in material development and quality control.
When submitting samples for HPLC Testing Services, including quantitative analysis, qualitative analysis, impurity detection, purity assessment, method development, or stability studies, please complete the Sample Submission Form.
We support pharmaceutical and biotech clients with reliable analytical solutions for drug development, compound characterization, and quality control, ensuring their R&D and production needs are met efficiently.
Our services help chemical manufacturers maintain consistent product quality, detect impurities, and verify compound composition across various production batches.
We partner with academic and research organizations to provide high-precision HPLC testing for experimental studies, method development, and compound profiling, supporting scientific discovery.
We assist food and supplement companies with ingredient analysis, contaminant detection, and mixture characterization, ensuring product quality and consistency.
Our HPLC services extend to industrial clients requiring detailed analysis of polymers, additives, and specialty chemicals, aiding in material innovation and production control.
We provide flexible and cost-effective HPLC testing solutions for small laboratories and startups, supporting early-stage research, method validation, and product development with professional guidance and reliable results.
Clients submit their samples with basic information on composition, quantity, and intended analysis. Our team provides guidance to ensure proper handling, storage, and preparation for optimal testing outcomes.
Each sample undergoes an initial evaluation to determine its characteristics, potential challenges, and the most suitable HPLC method for accurate analysis.
Based on the assessment, our experts develop or optimize HPLC methods, selecting appropriate columns, mobile phases, and detection settings tailored to each sample.
Samples are analyzed using advanced HPLC systems, ensuring high resolution, sensitivity, and reproducibility across all measurements.
Raw chromatograms and detector signals are carefully processed and analyzed using professional software to ensure accuracy and clarity of results.
Comprehensive reports, including chromatograms, quantitative data, impurity identification, and actionable recommendations, are delivered to clients for decision-making.
Our HPLC testing reports include the following content to fully support your analytical needs.
All measured compounds are summarized in detailed tables, presenting concentrations, peak areas, and relative distributions for easy reference.
We provide high-resolution chromatograms illustrating sample separation, peak profiles, and retention times, forming the basis for accurate interpretation.
Each report outlines the HPLC method used, including mobile phase, column, flow rate, and detection parameters, ensuring reproducibility and transparency.
Ideal for quantitative analysis of compounds absorbing in the ultraviolet and visible ranges.
High-sensitivity detection for compounds exhibiting natural or derivatized fluorescence.
Suitable for non-UV active compounds and polymer characterization.
Enables detection of semi-volatile or non-volatile components.
Provides precise molecular weight determination and structural confirmation.
Detects redox-active analytes with high selectivity and sensitivity.
Automated injection systems and advanced software enable reproducible analysis, efficient throughput, and accurate data processing.
A wide range of HPLC columns, temperature-controlled compartments, and supporting instruments ensures flexible method development and robust analysis.
We leverage a wide array of HPLC detectors and auxiliary equipment to provide precise, reliable, and versatile analysis.
Our scientists bring decades of combined experience in analytical chemistry, method development, and problem-solving.
We tailor our services to meet diverse client needs, from routine testing to challenging complex analyses.
We collaborate with leading suppliers, research institutes, and industry partners to maintain cutting-edge technologies and continuously improve our capabilities.
Every analysis is conducted under rigorous quality controls to ensure reproducibility, accuracy, and client confidence.
We provide personalized consultation, technical guidance, and responsive service to support informed decision-making.
Access essential chromatography resources, including guidance on column selection, mobile phase optimization, method setup, data interpretation, and detector usage tips.
Fill in your contact information to download the PDF whitepaper or request a personalized quote for your chromatography testing project.
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Client: A mid-sized pharmaceutical company in North America
Challenge: The client needed to accurately detect and quantify trace impurities in a new drug candidate to ensure high-quality production and robust analytical data. Complex sample matrices required highly sensitive and selective analysis.
Solution: BOC Sciences applied HPLC-MS techniques, optimizing separation parameters and MS detection settings for maximal sensitivity. Multiple sample preparation strategies and tailored columns were used to resolve overlapping peaks. Comprehensive chromatograms and quantitative impurity reports were delivered with actionable insights.
Outcome: The client achieved precise impurity profiling, reduced analytical uncertainty, and accelerated their quality control workflow, enabling confident decision-making in drug development.
Client: A natural product research institute in Asia
Challenge: The client required detailed structural analysis of bioactive compounds in complex botanical extracts, where standard HPLC alone could not provide sufficient structural information.
Solution: BOC Sciences integrated HPLC-NMR for simultaneous separation and structural elucidation. Optimized gradient programs, NMR detection parameters, and targeted fraction collection were applied to each extract. High-resolution spectra and purified compound data were provided in a comprehensive report.
Outcome: The client obtained reliable structural assignments for multiple bioactive compounds, improving their research efficiency and supporting publication-quality data generation.
Client: A European nutraceutical manufacturer
Challenge: The client required sensitive detection of trace heavy metals in a complex dietary supplement formulation, with high reproducibility and minimal interference from the matrix.
Solution: BOC Sciences employed HPLC-ICP-MS, carefully selecting columns and mobile phases to separate target metals while optimizing ICP-MS parameters for maximal sensitivity. Data processing and reporting included quantitative tables and compliance-friendly visualization.
Outcome: The client achieved precise and reliable trace element measurements, strengthened product safety assurance, and gained greater confidence in quality control processes.
The HPLC test for drugs is an analytical method that employs high-performance liquid chromatography to separate and quantify pharmaceutical compounds. It is commonly applied to assess drug purity, identify active ingredients, and monitor degradation products or metabolites.
HPLC testing is recognized for its high accuracy and reproducibility. It can distinguish compounds with similar structures and detect them at low concentration levels. With proper calibration and optimized methods, HPLC ensures precise and consistent measurement of drug components.
HPLC stands for High-Performance Liquid Chromatography. It is a powerful separation technique that uses high-pressure pumps to pass liquid solvents and samples through a packed column, enabling effective compound resolution and detection.
In pharmaceuticals, HPLC is widely used to analyze drug formulations, determine content uniformity, evaluate stability, and detect impurities. It supports every stage of the drug lifecycle, from early development research to manufacturing quality control.
HPLC is preferred because of its versatility, sensitivity, and broad applicability. It can analyze small molecules, peptides, and complex mixtures with high precision. Compared with many other techniques, HPLC offers faster analysis, robust quantification, and adaptability to diverse pharmaceutical applications.
BOC Sciences provides HPLC testing services, including drug content quantification, impurity analysis, metabolite detection, and stability studies, delivering reliable data to support clients' research and production needs.
The HPLC testing service from BOC Sciences consistently provides precise and interpretable data. Their methodical approach to chromatography analysis has greatly supported our experimental planning and internal research strategies.
— Dr. A., Senior Scientist, Specialty Chemical Company
BOC Sciences' HPLC testing team demonstrates exceptional skill in developing and optimizing analytical methods. Their innovative solutions have allowed us to explore new experimental avenues with confidence.
— Dr. B., Head of R&D, Biotech Startup
The HPLC testing services deliver comprehensive data that offers actionable insights for our research projects. The team's expertise in data interpretation has strengthened our internal experimental design.
— Dr. C., Research Manager, Chemical Innovation Firm
BOC Sciences provides highly consistent HPLC results with detailed data visualization. Their professional approach to analytical reporting has enhanced our understanding of complex research workflows.
— Dr. D., Principal Scientist, Materials Science Company
