Through its toxicology analysis services, BOC Sciences evaluates the safety profiles of pharmaceutical and biotechnological products throughout their development stages. We perform comprehensive toxicity studies that evaluate acute through chronic effects as well as genotoxic and organ-specific toxicity using validated in vitro and in vivo models. Our services produce high-quality reproducible data through the use of advanced technology platforms including LC-MS/MS, flow cytometry, and high-content imaging. Our toxicology experts design tailored study protocols that incorporate predictive toxicology tools and mechanistic knowledge to provide swift actionable insights that support decision-making processes in drug development.
Toxicology analysis serves as an essential part of drug development because it provides crucial information about the safety features of new chemical or biological entities. Potential toxic effects undergo systematic evaluation which facilitates early adverse outcome detection as well as identification of target organs affected by toxicity and understanding of dose-response relationships. The collected data plays a crucial role in enhancing compound selection processes while optimizing formulation strategies and reducing downstream attrition risks. Toxicology studies perform dual roles by detecting specific safety hazards including off-target toxicity and immunotoxicity while enhancing knowledge about how compounds interact with biological systems. Regular toxicology analysis during R&D enhances decision-making quality and development efficiency while maximizing the chances of selecting safe candidates for further development.
We have an experienced and highly skilled team of toxicology experts who provide accurate testing and professional technical support to our clients.
We offer tailored toxicology testing plans based on the specific needs of our clients, ensuring that the tests align closely with the project goals.
Our use of current in vivo and in vitro models combined with sophisticated analytical methods provides accurate and reliable test results with enhanced efficiency.
Our services cover various testing areas, including acute toxicity, chronic toxicity, carcinogenicity, genotoxicity, and more, catering to diverse client needs.
We provide not only experimental data but also in-depth analysis and interpretation, helping clients make informed, science-based decisions.
We are committed to delivering high-quality test reports on time, ensuring that clients receive key data promptly to accelerate their research and development processes.
BOC Sciences offers a full suite of toxicology testing services to support the non-clinical safety evaluation of drug candidates across therapeutic modalities. Our in vitro and in vivo studies are designed to systematically assess toxic effects under various exposure conditions, helping sponsors characterize compound liabilities, optimize candidate selection, and de-risk development pipelines. These services are applicable to small molecules, biologics, and complex formulations, delivering high-quality, reproducible data aligned with industry best practices.
Evaluates the adverse effects of a single or short-term exposure to a compound, providing initial safety thresholds and helping determine the median lethal dose (LD50).
Assesses toxic effects over repeated dosing periods (typically 28 to 90 days) to support identification of target organ toxicity and dose-response relationships.
Investigates long-term toxicological outcomes following extended compound administration, critical for supporting prolonged therapeutic use.
Determines a compound’s potential to induce cancer or promote tumor development over time, using rodent models and histopathological evaluations.
Screens for genetic mutations using assays such as Ames test and chromosomal aberration analysis to evaluate genotoxic potential.
Examines adverse effects on fertility, reproductive performance, and embryonic development, including teratogenicity and prenatal toxicity.
Provides a broader evaluation of heritable genetic alterations through assays such as micronucleus and comet tests, supporting genome integrity assessment.
Assesses structural and functional impacts on the nervous system using behavioral, histological, and biomarker endpoints to evaluate central and peripheral neurotoxicity.
At BOC Sciences, we provide comprehensive in vitro and in vivo models to support toxicology analysis and safety profiling. Our diverse range of models allows for accurate evaluation of toxicity and potential risks associated with compounds. With advanced platforms and a dedicated team of experts, we ensure reliable and reproducible results for researchers seeking to assess safety during the early stages of development. Our models cover a wide array of applications, from acute to chronic toxicity assessments, and are suitable for various industries, including pharmaceuticals, cosmetics, food safety, and more.
| Primary Cells | Immune Cell Models |
| Tumor Cell Lines | Neuronal Cell Models |
| Mouse Models | Zebrafish Models |
| Rabbit Models | Guinea Pig Models |
BOC Sciences utilizes cutting-edge analytical platforms to provide precise and reliable toxicology testing services. Our advanced technologies enable detailed and accurate analysis of toxicological properties, helping to assess the safety profile of substances and compounds in various stages of research and development. By employing state-of-the-art platforms such as ELISA, GC-MS, HPLC, UV-Vis, PCR, XRD, AAS, and IR, we ensure high sensitivity, reproducibility, and accuracy in our testing processes. These technologies are designed to meet the diverse needs of toxicology studies, including detecting trace amounts of toxic substances, understanding their behavior in different environments, and supporting risk assessments. At BOC Sciences, we are dedicated to providing comprehensive data to help clients optimize safety profiles and accelerate the development of safe, effective products.
| ELISA | PCR |
| GC-MS | XRD |
| HPLC | AAS |
| UV-Vis Spectroscopy | IR |
BOC Sciences provides a broad range of toxicology testing services across various types of substances, supporting early-stage research and development, safety evaluations, and hazard identification. Utilizing advanced in vivo and in vitro models, along with high-sensitivity analytical platforms, we conduct comprehensive assessments of acute, subchronic, chronic, and specialized toxicity endpoints, delivering precise data that aids in the safe and effective development of chemical and pharmaceutical products.
We offer toxicological evaluations for psychoactive substances with different pharmacological properties. Our testing helps identify risks associated with the substance's potential to cause behavioral changes, toxicity in different organ systems, and other adverse effects.
Our services cover a wide range of therapeutic compounds, evaluating their effects on various biological systems. These evaluations include organ toxicity, genotoxicity, reproductive toxicity, and systemic adverse effects, assisting in optimizing compounds for further development.
We assess the toxicity of environmental pollutants, including pesticides, flame retardants, and heavy metals. Our testing supports the understanding of their long-term environmental impact and potential hazards to human health.
Our testing for volatile organic compounds covers different exposure routes, such as inhalation, ingestion, and dermal absorption, to evaluate potential toxic effects on organs and systems. This includes assessing both acute and chronic exposure risks.
We provide toxicity testing for gases, focusing on the effects of exposure on the respiratory, cardiovascular, and nervous systems. Our services are designed to simulate real-world exposure scenarios and assess the potential long-term impact on health.
We specialize in the evaluation of toxins derived from natural sources, including venom and bacterial toxins. Our testing includes assessing their systemic effects, immune system interference, and damage to target organs.
We conduct thorough toxicological assessments of emerging synthetic psychoactive substances, examining their effects on the nervous system, behavior, and potential for toxicity. These evaluations help identify risks related to abuse and long-term health effects.
We also offer testing for specialized substances such as radioactive materials and industrial chemicals linked to chronic exposure risks. Our testing focuses on the potential health effects associated with long-term exposure and the identification of harmful cumulative effects.
Customer Requirement Communication
We begin by discussing the client's research objectives, sample types, and requirements, ensuring a clear understanding of their needs for effective test planning.
Customized Plan and Quotation
Based on the client's needs, we provide a tailored toxicology testing plan and offer an accurate quotation according to project scope and complexity.
Sample Submission and Confirmation
After the testing plan is confirmed, the client submits samples. We verify that the samples meet requirements and prepare them for analysis.
Toxicology Testing Implementation
We conduct in vivo and in vitro tests based on the plan, assessing acute, subchronic, and chronic toxicity to ensure accurate and reliable results.
Data Analysis and Result Evaluation
We analyze test data in detail, assessing toxicity effects, dose-response relationships, and organ toxicity, and prepare a preliminary report for client review.
Report Delivery and Follow-up Support
We deliver a comprehensive report with test results and recommendations, offering ongoing support to ensure the client's understanding and application of findings.
At BOC Sciences, we offer a wide range of toxicology analysis services across various industries. Our services cover drug development, cosmetics, environmental monitoring, pesticides, food safety, and more. Whether your project involves new drug development, consumer products, or environmental assessments, we provide expert testing support. Below is an overview of the key areas where our toxicology analysis services are applied.
| Service Area | Service Description |
| Drug Development and Research | Evaluate the safety of new drug candidates, identify potential side effects, predict human safety, and optimize dosage and formulation. |
| Cosmetics and Personal Care | Assess the safety of cosmetics and personal care products on skin, eyes, and other body parts. |
| Pesticides and Fertilizers | Conduct toxicology testing on pesticides and fertilizers to ensure their safety for agricultural use, and assess their impact on non-target organisms, the environment, and human health. |
| Food Safety | Evaluate the toxicity of food additives, pesticide residues, and other chemical ingredients in food to ensure no adverse long-term effects on consumer health. |
| Chemicals and Industrial Products | Perform toxicology analysis on chemicals and industrial products such as plastics, paints, and cleaning agents to ensure their safety during production, use, or disposal, ensuring worker safety and environmental protection. |
| Novel Psychoactive Substances (NPS) | Conduct toxicology testing on novel psychoactive substances to assess potential risks to human health. |
| Vaccines and Biologics | Assess the toxicological properties of vaccines and biologics to ensure their safety and efficacy for human use. |
What is a toxicological analysis?
Toxicological analysis represents a scientific assessment that investigates how substances might negatively impact living beings. Toxicological analysis identifies toxicity levels and determines which organs are affected while assessing potential risks from chemical compounds as well as drugs and environmental pollutants. The analysis serves as a critical process for detecting safety issues prior to exposing humans or animals to substances.
What are the different types of toxicology tests?
Toxicology tests encompass multiple categories such as acute toxicity, chronic toxicity, carcinogenicity, genotoxicity, reproductive toxicity, and neurotoxicity. The varied tests target distinct toxicological parameters to evaluate the compound's general safety and its effects on human well-being during different exposure times.
How is toxicology analysis conducted?
Toxicology analysis is typically conducted through in vivo (animal studies) and in vitro (cell culture) testing methods. These tests evaluate how substances affect organisms at different levels, from cellular damage to systemic toxicity. Advanced technologies such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) are often used to analyze samples and detect harmful substances.
What are the benefits of conducting toxicology analysis early in the research phase?
Conducting toxicology analysis early in the research phase helps identify potential risks at an early stage. It provides valuable data for informed decision-making, facilitates better formulation optimization, and helps prevent the development of unsafe compounds. Early toxicology testing also reduces the likelihood of encountering obstacles, ensuring a more efficient and streamlined development process.
