Purity Studies

Purity Studies

Purity studies is a method that depends on properties and chemical reaction to analyze the purity of the substance, since the presence of impurities in drug substance is an extremely critical issue and can have a significant impact on the quality and safety of the drug. The International Conference of Harmonization (ICH) guidelines indicate that unknown impurities at or above 0.10% in the drug substance depending on the maximum daily dosage, should be characterized. It is the most concerning task in the modern pharmaceutical analysis to manufacturing high-quality drug. According to the clinical trials of drugs, the presence of small amounts (0.01-0.1%) of a highly mutagenic impurity produced positive mutagenicity results, therefore, the need to assess for chemical purity of drug components before the drug is formally put into use. Purity study plays an important role in the drug researches.

Below is a list of our technology for purity studies (including but not limit following):

Purity Studies

Gas chromatography-mass spectrometry (GC-MS)

We use this system to separate and identify most compounds. We used this technique for the first time screening analysis to detect compounds. We also use GC-MS to quantify cocaine, amphetamine, benzodiazepines, cannabis and other drugs.

With this system, we can quantify substances that can be degraded at high temperatures, such as LSD or Modafinil. We can also quantify drugs that require high-precision technology, such as fentanyl.

This process is used to calculate the molecular weight of a compound and perform a pyrolysis technique to detect substances that are not recognized by GC-MS. This technique is used to study new compounds and identify any uncertain results.

We use HPLC, linked to ultraviolet detector (HPLC-UV) mainly for quantitative LSD.

This technique is used for the quantification of MDMA and 2C-B

Why Choose BOC Sciences?

We provide anonymous and confidential services where users can submit their drug samples for testing to understand their composition and purity, identify adulteration, and provide customized information from a harm reduction perspective. Scientists at BOC Sciences are adept at purity studies of drugs. We have the advanced analytical instruments and top experts in all analytical areas. We can provide rapid, reliable, safe and clean method in purity studies of drug, even if that is tiny amounts of a substance. Glad to hear your comments and look forward to cooperating with you.

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