Custom Synthesis

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Custom Synthesis

BOC Sciences offers a full range of custom chemical synthesis and manufacturing services for biotechnology, pharmaceutical, life science, chemical research and related industries. Synthesis is a series of chemical reactions carried out for the purpose of obtaining one or more organic molecules. As an integral part of drug discovery or other chemical industries, chemical synthesis plays an important role in the screening of numerous potential active ingredients.

Custom Synthesis

Our custom chemical synthesis services include, but are not limited to, following:

Active pharmaceutical ingredient (API) is the part of a drug product that produces primary therapeutic effects. Some kinds of dosage forms, such as the compound preparation, possess two or more active ingredients that is designed to treat different symptoms or integrate the synthetical effects.

Chiral synthesis, also known as enantioselective synthesis, has a great importance in the screening of APIs and development of bio/pharmaceutical products.

Recognizing the increasing importance of radiometric detection in drug discovery and development, radiolabeled chemical synthesis is hence become a highly concerned area in the pharmaceutical industry.

Bioconjugation represents the technique of giving a target substance with certain desired properties through the site-specific reaction between the biomolecules and exogenous moieties (usually one or several other molecules). Through such covalent linkage approach, a broad range of innovative drug substances or end products are designed to improve the accuracy of disease diagnosis, pharmacokinetic properties, treatment efficacy and many other aspects.

An effective process R&D is an essential part of your drug development while it plays important role in controlling costs, ensuring product’s quality and meeting the requirements of regulations. More importantly, package solutions are available to address any problems and potential risks that significantly impact the quality of your products.

Chemical reactions are the processes by which chemicals interact to form new chemicals with different compositions. Simply stated, a chemical reaction is the process where reactants are transformed into products. How chemicals react is dictated by the chemical properties of the element or compound-the ways in which a compound or element undergoes changes in composition.

Polycyclic Aromatic Hydrocarbons Synthesis

Nucleosides & Nucleotides Synthesis

Carbohydrate Synthesis

Peptide Synthesis

Steroids Synthesis

Flavors-fragrance Synthesis

Semi-synthesis and Total Synthesis of Natural Products

Why BOC Sciences?

  • Synthetic Route Design and Optimization
  • Process Research, Development, and Optimization
  • Small- and Large-Scale Chemistry Capabilities
  • Advanced Synthetic and Analytical Platform
  • Expert Project Management
  • Cost-Effectiveness and High Efficiency

Common chemical reaction type

Michael additionFriedel-Crafts reaction
Stille CouplingHigh-pressure hydrogenation
Suzuki CouplingAsymmetric hydrogenation
Chiral SynthesisHeterocyclic formation
FluorinationOxidation/Reduction

Custom synthesis chemical documents are available:

Synthesis procedure (original synthesis records, TLC, etc), high performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic resonance analyses (NMR), etc.

Custom process

Custom Synthesis

References

  1. Piletsky, S., Piletska, E., Karim, K., Foster, G., Legge, C., & Turner, A. (2004). Custom synthesis of molecular imprinted polymers for biotechnological application: Preparation of a polymer selective for tylosin. Analytica chimica acta504(1), 123-130.
  2. Blackburn, G. M., Cherfils, J., & Moss, G. P. (2018). A critical review of the proposed definitions of fundamental chemical quantities and their impact on chemical communities (IUPAC Technical Report). Chemistry International.
  3. Tyson, R. (1988). Custom synthesis and process development. Chemistry and Industry, 118-22.
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