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Custom Synthesis

Synthesis is a series of chemical reactions carried out for the purpose of obtaining one or more organic molecules. As an integral part of drug discovery or other chemical industries, chemical synthesis plays an important role in the screening of numerous potential active ingredients. However, the chemical synthesis is always challenged by the properties of time-consuming and complex for the synthesis process, which leads to high content of impurities and low yield. Therefore, an efficient custom synthesis of high quality and complex lead compounds is essential in drug development.

Available Custom Synthesis Services

Active pharmaceutical ingredient (API) is the part of a drug product that produces primary therapeutic effects. Some kinds of dosage forms, such as the compound preparation, possess two or more active ingredients that is designed to treat different symptoms or integrate the synthetical effects.

Chiral synthesis, also known as enantioselective synthesis, has a great importance in the screening of APIs and development of bio/pharmaceutical products.

Recognizing the increasing importance of radiometric detection in drug discovery and development, radiolabeled chemical synthesis is hence become a highly concerned area in the pharmaceutical industry.

Bioconjugation represents the technique of giving a target substance with certain desired properties through the site-specific reaction between the biomolecules and exogenous moieties (usually one or several other molecules). Through such covalent linkage approach, a broad range of innovative drug substances or end products are designed to improve the accuracy of disease diagnosis, pharmacokinetic properties, treatment efficacy and many other aspects.

An effective process R&D is an essential part of your drug development while it plays important role in controlling costs, ensuring product’s quality and meeting the requirements of regulations. More importantly, package solutions are available to address any problems and potential risks that significantly impact the quality of your products.

Chemical reactions are the processes by which chemicals interact to form new chemicals with different compositions. Simply stated, a chemical reaction is the process where reactants are transformed into products. How chemicals react is dictated by the chemical properties of the element or compound-the ways in which a compound or element undergoes changes in composition.

Custom Synthesis

  • Polycyclic Aromatic Hydrocarbons
  • Nucleosides & Nucleotides
  • Carbohydrate synthesis
  • Peptide Synthesis
  • Steroids Synthesis
  • Flavors-fragrance Synthesis
  • Semi-synthesis and Total Synthesis of Natural Products

Why Choose BOC Sciences?

BOC Sciences provides high-quality, low-cost, high-tech products to customers around the world. We has employed a dedicated staff of professional chemists to help you develop the most efficient process for synthesis of complex drug substances. With diverse state-of-the-art technologies and approaches, clients’ synthetic route can be developed and optimized in the most cost effective way. Each step of product synthesis is subject to BOC Sciences’ stringent quality control. Typical delivery specifications include:

  • In quantities of several milligrams up to 100 grams.
  • Additional analyses, such as stability determination, impurity analysis, and residual solvents etc.
  • With diverse state-of-the-art technologies and approaches.
  • Quality assurance: HPLC chromatogram and Mass spec analysis.
  • Overnight shipping with suitable packs.

At BOC Sciences, our customers will be resourced with various kinds of synthetic and analytical instrumentations. Our experts will work with you to optimize the synthetic route and approaches. Additionally, according to your needs and the properties of chemical substances, a wide range of custom services are available in our laboratory. If you would like BOC Sciences to help you synthesis your products, please contact us!

References

  1. Piletsky, S., Piletska, E., Karim, K., Foster, G., Legge, C., & Turner, A. (2004). Custom synthesis of molecular imprinted polymers for biotechnological application: Preparation of a polymer selective for tylosin. Analytica chimica acta504(1), 123-130.
  2. Blackburn, G. M., Cherfils, J., & Moss, G. P. (2018). A critical review of the proposed definitions of fundamental chemical quantities and their impact on chemical communities (IUPAC Technical Report). Chemistry International.
  3. Tyson, R. (1988). Custom synthesis and process development. Chemistry and Industry, 118-22.
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